
ISOLUTE® PE-AX is a strong anion exchange sorbent used to extract acidic analytes from aqueous samples.
Chemical description | Quaternary amine (non-endcapped) functionalized silica with acetate counter ion. Manufactured using a trifunctional silane. |
Sorbent type | Strong anion exchange |
Average particle size | 50 µm |
Pore diameter | 60 Å |
Exchange capacity | 0.6 meq/g |
This Chemistry Data Sheet details the use of ISOLUTE PE-AX, a strong anion exchange sorbent, for the
purification of acidic products from organic synthesis mixtures containing non-acidic reagents or by-products.
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Product Notes
In this catalog product information is displayed with easy-to-follow application details and supporting documentation. Ordering information is found following each product listing.
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QuickStart Guide to SPE
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Manuals & User Guides
The first decision that needs to be made is what the final analysis will be for the analyte. This will have an impact on the sample and cartridge size, as well as the final elution solvent. Gas chromatography offers higher sensitivity than HPLC, while HPLC is better suited for ionisable species and very high molecular weights. If LC-MS is available, minimal sample clean-up may be required.
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Laboratory chemical
Not for therapeutic or diagnostic use
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Material Safety Data Sheets
ISOLUTE P. E. – A. X.
9503
Laboratory chemical
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Material Safety Data Sheets
The ISOLUTE® family of anion exchange sorbents are used to extract organic anions (acid compounds capable of exhibiting a negative charge) from both aqueous and non-aqueous matrixes. This technical
note describes their use for aqueous matrices only. Although extraction using these sorbents is by the same mechanism, each has properties which influence the way they are used.
Tags: English,
Product Notes
This Chemistry Data Sheet details the use of ISOLUTE PE-AX, a strong anion exchange sorbent, for the
purification of acidic products from organic synthesis mixtures containing non-acidic reagents or by-products.
Tags: Application Notes,
Product Notes
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Question:
What is the maximum capacity of an SPE column?
Answer:
The capacity of a sorbent is defined as the total mass of strongly retained analyte that can be retained by a given mass of the sorbent under optimum conditions.
For most sorbents, this can range from 1-5% by weight. 100 mg of sorbent might retain 1-5 mg of analyte.
Ion exchange sorbents typically have a capacity of 0.3-1 meq/g.
Browse more questions and answers >
ISOLUTE® PE-AX is a quaternary amine bonded sorbent used for the extraction of acidic compounds from aqueous (or partially aqueous) samples. It keeps a permanent positive charge across the pH range. Analytes are eluted from ISOLUTE PE-AX by eliminating the charge on the analyte (low pH), so this sorbent is not suitable for extraction of strong acids. ISOLUTE PE-AX is supplied with an acetate counter ion for more efficient extraction of acidic analytes including those with highly polar/water soluble characteristics.
ISOLUTE PE-AX is available in a wide range of SPE column formats.
ISOLUTE PE-AX is also available as loose sorbent (100g pack).
Part No. | Description | Product type | Pack Size | Price | ||
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503-0002-A | ISOLUTE® PE-AX 25 mg/1 mL | Consumables | 100 | Log in for price | |
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503-0010-A | ISOLUTE® PE-AX 100 mg/1 mL | Consumables | 100 | Log in for price | |
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503-0010-B | ISOLUTE® PE-AX 100 mg/3 mL | Consumables | 50 | Log in for price | |
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503-0010-C | ISOLUTE® PE-AX 100 mg/6 mL | Consumables | 30 | Log in for price | |
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503-0020-B | ISOLUTE® PE-AX 200 mg/3 mL | Consumables | 50 | Log in for price | |
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503-0050-B | ISOLUTE® PE-AX 500 mg/3 mL | Consumables | 50 | Log in for price | |
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503-0050-C | ISOLUTE® PE-AX 500 mg/6 mL | Consumables | 30 | Log in for price | |
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503-0100-C | ISOLUTE® PE-AX 1 g/6 mL | Consumables | 30 | Log in for price | |
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503-0200-D | ISOLUTE® PE-AX 2 g/15 mL | Consumables | 20 | Log in for price |