Sample preparation using ISOLUTE® PPT+ Protein Precipitation Plates is fast and simple.
The optimized filtration system in ISOLUTE PPT+ plates provides an easy to automate solution for efficient protein removal from biological fluid samples. The procedure is streamlined, with no awkward off-line steps.
Part No. | Description | Pack Size | List Price | |
---|---|---|---|---|
120-2040-P01 | ISOLUTE® PPT+ Fixed Well Plate | 1 | 104 USD | Add to quote/cart |
ISOLUTE PPT+ plates use the solvent first procedure for maximised precipitation efficiency. The proprietary functionalized bottom frit holds up organic precipitation solvent while the plasma sample is added, maximizing contact time and giving the most efficient precipitation effect. No vortex mixing is required. The purified sample does not pass into the collection plate until vacuum or pressure is applied.
Unlike membrane based devices, the system has an optimized porosity distribution and acts as a depth filter, holding up the precipitated protein without well blockage.
Using the ‘solvent first’ methodology, ISOLUTE® PPT+ plates consistently produce clear filtrates. This reduces ion suppression and improves the accuracy of LC-MS/MS analysis compared to alternative protein precipitation procedures. Up to 96 samples containing acidic, basic or neutral drug compounds can be purified simultaneously in less than ten minutes.
ISOLUTE PPT+ is available in fixed well 96-well plate format. Process manually using the VacMaster™-96 Sample Processing Manifold or Biotage® PRESSURE+ 96 Positive Pressure Manifold. The simple procedure can be fully automated using Biotage® Extrahera or other 96-well liquid handling systems.
Biotage is a Global Impact Tech Company committed to solving society’s problems. We offer workflow solutions and products to customers in drug discovery and development and diagnostics, analytical testing and water and environmental testing.
Biotage is contributing to sustainable science with the goal to make the world healthier, greener and cleaner – HumanKind Unlimited.
Our customers span a broad range of market segments including pharmaceutical, biotech, diagnostic, contract research and contract manufacturers as well as clinical, forensic and academic laboratories in addition to organizations focused on food safety, clean water and environmental sustainability.
Biotage is headquartered in Uppsala in Sweden and employs appr. 700 people worldwide. The Group had sales of 1,566 MSEK in 2022 and our products are sold in more than 80 countries. Biotage’s share (BIOT) is listed in the Large Cap segment on the NASDAQ Stockholm.
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