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Automating large-scale plasmid DNA purification

 

The increasing demand for biologics discovery and gene therapy development has intensified the need for scalable, high-quality plasmid DNA production. Traditional large-scale purification methods, including maxi-, mega-, and giga prep workflows, rely on manual processing steps that can introduce variability, limit throughput, and affect downstream applications such as transfection and protein expression. 

In this webinar, together with The Scientist, Lee Hoang, Senior Field Application Scientist discusses automated approaches to large-scale plasmid purification and examines how integrated workflows, including chromatography-based purification and on-column concentration strategies, support consistent DNA yield and quality across multiple scales. 

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