Biotage® PS-Isocyanate is a scavenger resin that can readily scavenge excess nucleophiles, which are often used to drive reactions to completion. The reaction of nucleophiles with the isocyanate moiety occurs without liberation of small molecule by-products.
Part No. | Description | Pack Size | List Price | |
---|---|---|---|---|
800260 | Biotage® PS-Isocyanate, 10 g | 1 | 119 USD | Add to quote/cart |
800261 | Biotage® PS-Isocyanate, 25 g | 1 | 252 USD | Add to quote/cart |
800495 | Biotage® PS-Isocyanate, 3 g | 1 | 51 USD | Add to quote/cart |
Key facts and figures and quick at a glance usage data
For over 15 years Biotage has been guiding and leading the industry in supported reagents and scavengers.
Biotage® PS-Isocyanate is a polystyrene-bound scavenger, targeting nucleophiles such as amines and alkoxides. Resin-bound scavengers are added after a reaction is complete in order to quench and react selectively with excess reactants and/or reaction by-products. The resulting resin-bound adducts are removed by simple filtration.
PS-Isocyanate is a 1% cross-linked poly(styreneco-divinylbenzene) which has pendent benzylisocyanate functionality. The resin is produced from aminomethyl resin by a superior process which gives high conversion with minimal urea formation as determined by IR spectroscopy. The resin can readily scavenge excess nucleophiles, which are often used to drive reactions to completion. This facilitates workup and purification.1–5 The reaction of nucleophiles with the isocyanate moiety occurs without liberation of small molecule by-products.
More effective than traditional methods, polymer supported chemistry has been used widely in applications for over fifty years. Biotage supported reagents and scavengers are based on functionalized polystyrene or silica polymers and are 100% insoluble, therefore can be added to reactions and completely removed afterwards.
Key supplier to industry for over 15 years, used in numerous patents and cGMP process campaigns
From grams in research through to multi kilogram quantities in production campaigns.
The abrasion-resistant matrix has better handling characteristics and reduced transfer losses compared to other materials.
Inert, specifically-reactive and deployed to achieve a specific purpose. With lot control, QA / QC documentation, SDS, ISO 9001 / 14001 registration, BSE / TSE statement, shelf-life statement, these resins also support the audit trail.
SEL-2EV - Two Channel, Extended Collection Bed, UV Detector
Biotage is a Global Impact Tech Company committed to solving society’s problems. We offer workflow solutions and products to customers in drug discovery and development and diagnostics, analytical testing and water and environmental testing.
Biotage is contributing to sustainable science with the goal to make the world healthier, greener and cleaner – HumanKind Unlimited.
Our customers span a broad range of market segments including pharmaceutical, biotech, diagnostic, contract research and contract manufacturers as well as clinical, forensic and academic laboratories in addition to organizations focused on food safety, clean water and environmental sustainability.
Biotage is headquartered in Uppsala in Sweden and employs appr. 700 people worldwide. The Group had sales of 1,566 MSEK in 2022 and our products are sold in more than 80 countries. Biotage’s share (BIOT) is listed in the Large Cap segment on the NASDAQ Stockholm.
Copyright © 2023 Biotage