Biotage^® Flash 150 Systems

Biotage® Flash 150 systems safely operate at 100 psi enabling fast flow rates and the use of high viscosity solvents. Our proven radial compression technology ensures near zero “wall effects” and channelling inside each column. This maintains the bed’s stability, rendering cleaner, purer fractions in less time and higher overall product yield.  Flash 150 cartridges are so-called as they are 150 mm in diameter and routinely operate at flow rates up to 1000 mL/min.  These purification systems allow you to quickly scale-up and complete runs, saving hours or even days of purification time.

In a comparison between a Flash 150M cartridge (150 mm x 300 mm) and a 120 mm x 660 mm traditional glass column, fractions were collected in 7.2 hours using the glass column, while the Flash 150M cartridge required just 90 minutes. Additionally, the recovery ratio of product from the Flash 150M system was 4 times that of the glass column. This resulted in a plant saving nearly 4 weeks of development time.

The Biotage® Flash 150 system includes an easy-to-install radial compression module, a fully integrated gas manifold, solvent reservoir, sample injection module (SIM), a start-up kit with all necessary tubing, grounding kit, and a user’s manual.  Prepacked cartridges are ordered separately. Flash 150 compression modules are mounted onto robust portable bases (included in the system package), which are fitted with casters for easy mobility.