Alternative forensic matrices: Evaluation of simplified workflow for DoA extraction from nail samples

The testing of alternative matrices in forensic and/or clinical toxicology is gaining popularity, partly due to less invasive means of collection. Blood and urine testing are still by far more prevalent. However, traditional testing in combination with other matrices such as hair or nail can provide a more rounded picture of abstinence or abuse and associated timeframes. Solid matrix analysis by LC/MS or GC/MS is generally more involved due to the necessity of multiple manual labour steps to convert the sample into an extractable form. This poster aims to demonstrate workflow advantages for fingernail analysis; multi-sample homogenization, extraction and analysis for a range of drugs of abuse.

Literature number: P199.V.4