Historically, silica-based solid phase extraction (SPE) cartridges have been used for drugs of abuse testing, the exact choice being dependent on drug functionality. GC/MS sensitivity requirements traditionally dictated larger volume sampling resulting in the use of cartridges capable of accepting volumes up to 10 mL. Reduced sample size has been achieved due to increased specificity using GC-MS/MS or the movement to LC-MS/MS analysis. This poster will present a dedicated sample preparation platform capable of processing volumes associated with drugs of abuse testing whether using GC/MS or LC/MS end points.
