Comparing method performance for testing PFAS in aqueous samples: EPA 537.1, EPA 533, ISO 21675

Extraction protocols and analytical methods utilized for detecting Per-and polyfluoroalkyl substances (PFAS) in aqueous samples have evolved rapidly over the past decade. From 2013 –2015, EPA 537 was utilized for assessment monitoring of PFAS as part of the Unregulated Contaminant Monitoring Rule (UCMR) 3 program and was updated to EPA method 537.1, shortly thereafter. In late 2019, EPA method 533 and International Organization for Standardization (ISO) Method 21675 were released, which in addition to EPA method 537.1, enable laboratories to quantify up to 37 PFAS analytes with exceptional precision and accuracy. To better improve our understanding of method performance, it is beneficial to review these top methods utilized for evaluating PFAS in aqueous samples.  

Literature number: P252