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    Join us at ASMS 2025

    Are you attending the ASMS Annual Conference in Baltimore, MD from June 1-5?

    Stop by booth #841 to learn about our sample preparation workflows, plus biomolecule and peptide purification solutions! 

    🎉 Get Ready for an Action-Packed Week! 🎉

    • Fuel up & get inspired at our Breakfast Seminar – Monday, June 2
    • Discover cutting-edge ideas at our Poster Sessions happening all week (details below!)
    • Game on! Play for a chance to win exciting raffle prizes

     

    Schedule of events

    Breakfast seminar:
    Overcoming Sample Prep Challenges in Oligonucleotides LC-MS/MS Analysis

    Calendar   Monday, June 2, 2025    Time   7:00am - 8:15am in Room 320

    Oligonucleotide therapeutics have emerged as promising drug candidates due to their high specificity in targeting various genetic diseases and disorders. Despite advances in LC-MS, the inherent complexity, charge properties, and susceptibility to degradation make oligonucleotide quantitation in biological matrices particularly challenging. Effective sample preparation is essential to mitigate matrix effects, enhance analyte recovery, and ensure data reproducibility.

    This seminar will discuss practical sample preparation strategies to improve matrix cleanup and extraction efficiency for oligonucleotides bioanalysis. We will demonstrate how these strategies achieve consistent recovery and strengthen overall method robustness.

     

    lee williams circle

    Presenter:

    Lee Williams, PhD
    Director of Analytical Products & Applications R&D 

    Lee Williams has earned his PhD in mass spectrometry from the University of Wales, Swansea and completed a Post-Doc in the Biochemical Toxicology department at the National Center for Toxicological Research, FDA labs. Lee joined Biotage (Formerly Argonaut) to advance the LC/MS capability within the sample preparation arena. Over the 18 years he has occupied a variety of roles from senior scientist, group leader, lab manager and most recently as the Director of R&D for Analytical Consumables and Applications.  

    Please sign up here:

    Poster presentations

    Sample Preparation for the Determination of an Extended Panel of Per- and Polyfluoroalkyl Substances (PFAS) from Human Serum using UHPLC-MS/MS
    Geoff Davies, PhD | Monday, June 2

    Sample Cleanup Approaches for LC-MS/MS Analysis of a Multi-Class Drugs of Abuse Panel in Breast Milk
    Kyle Dukes, MSc | Tuesday, June 3

    Evaluation of Novel Solid Phase Extraction for the Determination of Oligonucleotides from Biological Matrices and Analysis using UPLC-MS/MS
    Lee Williams, PhD | Wednesday, June 4

    Sample Matrix Cleanup using Protein and Phospholipid Depletion Technique (PLD) for Drugs of Abuse LC-MS/MS Analysis in Whole Blood
    Sohel Rana, PhD | Wednesday, June 4

    Simultaneous Quantification of Pesticide Residues in Olive Oil via LC-MS/MS and GC-MS/MS Using a Streamlined, Automatable cSPE Clean-up Workflow
    Geoff Davies, PhD | Thursday, June 5

    Automated Sample Extraction Technique for LC-MS/MS Analysis of Zolmitriptan in Plasma
    Esraa AboJasser | Thursday, June 5

    Related resources

    Biotage-PhyTip-PTR920518l

    Biomolecule Purification
    Biotage-Extrahera-Classic-Front-GLP (1)

    Sample Prep Automation
    biotage-peptiren-parallel-peptide-purification

    Parallel Peptide Workflow
    Biotage-TurboVap96-Dual-Screen-Center

    Evaporation

    About Biotage

    Biotage is the Global Go-To Separations Company, supporting customers from drug discovery and development through to diagnostics and analytical testing with intelligent and sustainable workflow solutions. Our expertise and top-tier separation solutions play a key role in streamlining our customers’ workflows and improving their outcomes. Headquartered in Sweden, Biotage operates globally with 700 employees, serving over 80 countries. Our company is listed on NASDAQ Stockholm (BIOT).

    Copyright © 2025 Biotage

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    ASMS 2025