Biotage^® Flash 75 Systems

Biotage® Flash 75 systems safely operate at 100 psi enabling fast flow rates and the use of high viscosity solvents. Our proven, patented radial compression technology ensures near zero “wall effects” and channelling inside each column. This maintains the bed’s stability, rendering cleaner, purer fractions in less time and higher overall product yield. Routinely operating at a flow rate of up to 250 mL/min, these purification systems allow you to quickly scale-up and complete runs, saving hours or even days of purification time.

In a comparison between a Biotage Flash 75L cartridge (75 mm x 300 mm) and a 110 mm x 200 mm traditional glass column, fractions were collected in 2.5 hours using the glass column, while the Flash 75L cartridge required just 40 minutes. Additionally there were fewer mixed fractions, resulting in greater product purity.

The system includes an easy-to-install radial compression module, a fully integrated air manifold, solvent reservoir, a start-up kit with all necessary tubing, grounding kit, and a user’s manual. Flash 75 systems come with a sample injection module (SIM) as standard, which helps to bridge the gap from lab to large scale method development. The SIMs (available in 100 mL, 500 mL, 1000 mL and 2000 mL) facilitates the handling of routine samples as well as viscous oils and samples with poor solubility.