Biotage® Flash 75 systems support flash purification up to 80% faster than traditional glass columns. There are simple, robust and reliable systems, containing everything needed to scale up purifications from the lab.
Flash 75 platforms fully embrace rock solid innovations in delivering robust and reliable large scale flash purification. Our broad selection of columns enables professionals to choose the solution which best suits their purification needs. Flash columns are available in a large variety of sizes from 5 g to 350 g for development purposes, and from 400g to 40Kg and in a range of media types for production.
Biotage® Flash 75 systems safely operate at 100 psi enabling fast flow rates and the use of high viscosity solvents. Our proven radial compression technology ensures near zero “wall effects” and channelling inside each column. This maintains the bed’s stability, rendering cleaner, purer fractions in less time and higher overall product yield. Routinely operating at a flow rate of up to 250 mL/min, these purification systems allow you to quickly scale-up and complete runs, saving hours or even days of purification time.
In a comparison between a Biotage Flash 75L cartridge (75 mm x 300 mm) and a 110 mm x 200 mm traditional glass column, fractions were collected in 2.5 hours using the glass column, while the Flash 75L cartridge required just 40 minutes. Additionally there were fewer mixed fractions, resulting in greater product purity.
The system includes an easy-to-install radial compression module, a fully integrated air manifold, solvent reservoir, a start-up kit with all necessary tubing, grounding kit, and a user’s manual. Flash 75 systems come with a sample injection module (SIM) as standard, which helps to bridge the gap from lab to large scale method development. The SIMs (available in 100 mL, 500 mL, 1000 mL and 2000 mL) facilitates the handling of routine samples as well as viscous oils and samples with poor solubility.
SEL-2EV - Two Channel, Extended Collection Bed, UV Detector