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This application note describes optimization for a fully automated synthesis and on-resin cyclization of oxytocin enabled by Branches™ , a unique software feature of the Biotage® Initiator+ Alstra™ pe...
Introduction Synthetic benzodiazepines are becoming more abused and are considered “legal highs”. Many forensic laboratories are finding more and more of these compounds in post-mortem and impairment ...
This technical note provides a detailed procedure for the preparation of PFAS compounds according to EPA method 537.1.
Figure 1: Structural formula of mycophenolic acid. Introduction Mycophenolic acid (Figure 1) is an active metabolite produced by the hydrolysis of the immunosuppressive agent Mycophenolate Mofetil in ...
Scope This application note will outline the appropriate methods for the extraction of dispersed oil in water in compliance with OSPAR and ISO9377-2 methods, using Biotage automated or manual SPE solu...
Introduction The DryDisk® Separation Membrane was designed to replace conventional sodium sulphate in the drying of sample extracts. The DryDisk® is a hydrophobic membrane, consisting of a GORE-TEX® p...
The ISOLUTE® family of cation exchange sorbents are used to extract organic cations (basic compounds capable of exhibiting a positive charge) from both aqueous and non-aqueous matrixes. Although extra...
Small-scale protein purification is an efficient method for screening samples for protein expression, stability, and functionality as well scaling down process development workflows for drug candidate...
Peptides have returned to the forefront of drug discovery efforts as unbiased screening technologies have improved and the rules defining passive cell permeability have been clarified. As a result, th...
Hydroxychloroquine (HCQ) and chloroquine (CQ) are common antimalarial drugs with long half-lives. They are currently being tested as potential treatments for COVID-19. Due to their high publicity in t...