New technologies enabling parallel purification of peptide libraries

Peptide drug discovery efforts are increasing as unbiased screening technologies have improved and strategies to evaluate passive cell permeability have been defined. As a result, the demand for synthetic peptide libraries has increased significantly. Chemists
tasked with delivering peptide libraries for evaluation, particularly in plate-based formats, encounter significant practical handling challenges not common during larger scale, lower throughput projects. Moreover, the purification bottleneck demands new
technologies that enable high-throughput purification ahead of library evaluation.

Literature number: P282