Literature
Showing posts tagged with "biologics-and-advanced-therapeutics"
High-throughput, automated large-scale plasmid purification: Eliminating manual bottlenecks in the therapeutic pipeline
The rapid expansion of biologics discovery – from high-throughput antibody screening to the development of viral vectors for gene therapy – has created an unprecedented demand for high-quality, transf...
Maximize antibody recovery with PrismA PhyTip® columns
Biotage PrismA PhyTip® columns leverage a unique combination of patented dual flow chromatography technology and Cytiva’s MabSelect PrismA ™ resin. This powerful pairing enables high throughput, small...
Biotage® PhyPrep method library info sheet: Reduced runtime for centrifuged samples
Simplify and shorten the standard method by removing the filtration step for customers opting to centrifuge their samples. When to use When centrifugation is the preferred clarification method, the fi...
PhyTip® columns selection guide
PhyTip® columns come with dual flow chromatography protocols that have been validated with real protein samples and can be used on all major automated liquid handling systems, enabling efficient set u...
Ion exchange PhyTip® Columns perform resin screening for most efficient capture of target proteins
PhyTip® Ion Exchange columns offer the unique ability to screen dierent wash and elution buers and a number of resins in a single experiment. Once Ion Exchange conditions have been optimized, they are...
Achieving transfection-grade DNA from automated Maxi, Mega, and GigaPrep scales using Biotage® PhyPrep
Clean plasmid DNA preparations are fundamental for many downstream applications in life science workflows. Processes such as transient transfection for production of antibodies and AAV production, gen...
Dual flow chromatography for process development
Functionalized pipette tips have been available for many years. Marketed for solid phase extraction, these pipette tips carry a solid phase contained within a polymer precipitate located at the end of...
Elevating protein purification efficiency: Transitioning from manual techniques to automated platforms
Small-scale protein purification is an efficient method for screening samples for protein expression, stability, and functionality as well scaling down process development workflows for drug candidate...
Enabling high-throughput functional characterization of therapeutic antibodies
Introduction The process of drug discovery over the last 50 years has seen momentous change1. In the 1950’s, lead molecules were found largely by serendipity through in vivo screening of the chemical ...