Literature

Summary Unbiased screening technologies have opened the door to expanded repertoires of peptides that can quickly and easily be screened in early lead identification programs, making this a much more ...

Abstract Analysis of drug panels in urine samples can be challenging, and the trend towards larger panels including multiple drug classes compounds the issues faced during method development. This whi...

Introduction Drug discovery and development is a multifaceted process which involves a long and exhaustive journey through basic research, discovery of the medicine, preclinical development tests, inc...

Abstract Analysis of drug panels in urine samples can be challenging, and the trend towards larger panels including multiple drug classes compounds the issues faced during method development. This whi...

Figure 1. Example analyte structures by class.

Whether you are utilizing manual or automated equipment, it is important to understand preparation technique throughout the extraction protocol. This procedure guide outlines a general extraction proc...

"Biotage® Extrahera™ Classic is a versatile platform, a great tool for method development,” says Jonathan Tang at the University of East Anglia about the Biotage® Extrahera™ Classic automated sample p...

Introduction This method was developed for the extraction of the tetrahydrocannabinol carboxylic acid metabolite (THC-COOH) from urine using a mixed non-polar and anion exchange retention mechanism. T...

Abstract An automated protocol was developed to perform dual flow chromatography using PhyTip® columns on the Opentrons OT-2 liquid handler. Two types of PhyTip® columns were tested: Ni-IMAC for His-t...

Introduction In chemical synthesis, heat is an essential ingredient. Some reactions require low temperatures, for example those that create large exotherms, but in the vast majority of synthetic proce...