Literature

On a scenic drive up the I-15 in southern California, we were able to take a tour of the undergraduate lab at California State University, San Marcos with Dr. Robert Lafe. His lab is one of the first ...

Synthetic peptide purification represents the most significant bottleneck of the entire peptide workflow. Reversed-phase flash chromatography is gaining traction as a strategy to reduce this bottlenec...

When it comes to chromatography, no two media are the same. Silica from one flash column manufacturer will likely be different from another due to their media source’s manufacturing process and raw ma...

Microwave synthesis provides an excellent method for vastly increasing the speed of chemical reactions in a safe and controllable way. In the educational environment, this means you can expose student...

Introduction Microwave irradiation is still the most effective solution for providing a fast, precise and efficient heating method for synthesizing peptides, peptoids, PNA and peptidomimetics with hig...

Introduction In the modern scientific environment, there is a constant desire to improve the speed and efficiency of processes in the development of new drugs, testing protocols and technologies. Comp...

Introduction Flash chromatography is the preferred purification technique of organic, medicinal, natural product chemists, and more recently peptide chemists because it has the power to separate a bro...

Summary Unbiased screening technologies have opened the door to expanded repertoires of peptides that can quickly and easily be screened in early lead identification programs, making this a much more ...

Introduction In chemical synthesis, heat is an essential ingredient. Some reactions require low temperatures, for example those that create large exotherms, but in the vast majority of synthetic proce...