Literature

Richard E. Johnsson, Ph.D. is Head of Peptide Chemistry at Red Glead Discovery in Lund, Sweden. Red Glead Discovery is a pre-clinical drug discovery CRO offering a broad range of services to Life Scie...

Genome Science Research Institute, Genome Science Research Department 1, Screening Group

Figure 1: PeptiDream Inc. relocated their head office in August 2017 and established its new research centre in the Kawasaki City International Strategic Centre. The expanded facility is expected to s...

The absence of impurities in peptides, synthesized via SPPS, is vital for reliable assay results. However, especially in drug discovery screenings (number of peptides > 24), potentially low-purity cru...

Introduction Synthetic lipids and lipid nanoparticles (LNPs) have been used for mRNA-based drug administration for several years. The lipid mixtures typically contain four compounds, including cholest...

Introduction High-throughput library synthesis is typically required in the early stages of the drug discovery process. Despite the many advances in automated peptide synthesis technologies, the limit...

Dr. Sean P. Bew is Associate Professor in Chemistry at the University of East Anglia, UK, where he specializes in medicinal chemistry, isotope labelling, aziridine chemistry and supramolecular natural...

Executive summary Peptides have garnered much attention in a variety of applications over the last few years, and interest only continues to grow. With improved synthetic strategies, peptides are now ...

Introduction Discovering new chemical entities (NCEs) or new molecular entities (NMEs) is costly and time consuming. One needs only to look at the top 15 global pharmaceutical companies to see how exp...

Introduction As environmentally responsible chemists we all want to reduce the chemical waste volume we generate in our daily research activities. While the chemicals we use are necessary for what we ...