Showing posts tagged with "small-molecules-and-synthetic-therapeutics"
Summary Solid phase extraction (SPE) is a commonly used method to clean up various types of samples before analyzing them using LCMS. It is also an effective way to improve the purity of crude synthet...
Peptide drug discovery programs have advanced to the clinic as the rules for small molecule-like transport and bioavailability have become more thoroughly understood. Macrocyclic peptides, in particul...
Peptides are well suited for use as tool compounds to interrogate biological systems and processes due to their chameleonic ability to mimic a potential protein partner within the biological system of...
Peptide drug discovery efforts are increasing as unbiased screening technologies have improved and strategies to evaluate passive cell permeability have been defined. As a result, the demand for synth...
I am Adrian Wünsche, a young scientist at the Helmoltz Zentrum Dresden Rossendorf (HZDR), and I am a Ph.D. student beginning my work in the Institute of Radiopharmaceutical Cancer Research under the s...
“We have been working with a Biotage® Initiator+ Alstra™ since January 2013. During this period, the instrument has proved both efficient and robust, enabling us to successfully accomplish a substanti...
Figure 1: Dr. Muth together with some of his graduate students, from left to right, Pamela Farrales (2nd year Master’s student in Pharamcology), Dipti Kanabar (2nd year Master’s student in Medicinal C...
Figure 1: Dr. Justin Anglin is Director and Medicinal Chemistry Leader at the Centre for Drug Discovery, Baylor College of Medicine Neurological Research Institute.
Biotage recently introduced the newly launched Biotage® Selekt Enkel flash purification system to the College of Charleston. Biotage® Selekt with its two column channels is a well-established leader i...