In this application note, we compare the amounts of a threecomponent
mixture that can be separated on columns of the
same size, 25 g, but with different Silica material: SNAP KP-Sil
(average 50 μm irregular particles), Sfär Silica (60 μm spherical
particles) and Sfär Silica HC (20 μm spherical particles) using a
Biotage® Selekt instrument. Tags: Application Notes
Part No: AN128Published: 20190.27 MBFormat: pdfDownload
When purifying molecules, maximizing your efficiency is critical
to your daily work. For us at Biotage, helping you to make the
most of your time is of paramount importance. That is why we
have designed a lean and compact automated flash system with
two column channels, so you can prepare channel two while
channel one is running. Tags: Brochures
Part No: PPS495Published: 20181.56 MBFormat: pdfDownload
Purification is a fundamental step in drug discovery. As
pioneers of automated flash purification, Biotage is your
ideal partner. When it comes to purification, here are five reasons to
Selekt Biotage. Tags: Brochures
Part No: PPS491Published: 20180.68 MBFormat: pdfDownload
User Case: Professor Roger Strömberg, Karolinska Institutet. One of Professor Strömberg’s projects at Karolinska Institutet
involves the synthesis of artificial nucleases and PNAzymes. In
2013, his research group acquired a Biotage® Initiator+ Alstra™
peptide synthesizer for making PNAs and peptides. Tags: Customer Cases
Part No: PPS410Published: 20150.7 MBFormat: pdfDownload
Flash purification involves a simple liquid chromatography technique
» Method development uses TLC as a way of deciding the parameters for the
» Isocratic separations are easiest to develop, but gradient separations are
» Software in the Isolera helps with conversion of an isocratic separation to
» It is possible with the Spektra software to run step gradients
» Loading options are dependent on the column type
» SNAP offers the most flexibility
» Care must be taken to choose the best loading option to get good
purifications Tags: Manuals & User Guides
Part No: Published: 20132.62 MBFormat: pdfDownload
Synthetic chemistry is hard enough; purifying the reaction product can be even more challenging. If your reaction mixture shows you made your target but also many byproducts, what do you do? You can resynthesize using different reaction conditions, use advanced work-up procedures, or you can purify using high-performance flash chromatography. Tags: Posters
Part No: P192Published: 20190.36 MBFormat: pdfDownload
Peptide purification via flash
chromatography has recently been demonstrated as a viable
alternative to the more standard HPLC methods currently
utilized. Flash chromatography offers peptide chemists the
advantage of significantly greater loading capacity reducing the
overall purification time but with a compromise of decreased
peak resolution. Herein we present several strategies that,
when implemented, allow for very high purity peptide samples
purified by flash chromatography. Tags: White Papers
Part No: PPS510Published: 20191.24 MBFormat: pdfDownload
Die Flash-Chromatographie ist die bevorzugte
Reinigungsmethode für organische Stoffe, Arzneimittel und
Naturstoffe. In jüngster Zeit hat sie auch die Peptidchemie
erobert, verfügt sie doch über die Fähigkeit, eine Vielzahl
unterschiedlicher Verbindungen effizienter zu trennen, als dies
mit anderen Vorreinigungsverfahren wie z. B. dem Ausfällen
(Protein-Crash) oder der Flüssig-Flüssig-Extraktion möglich ist.
Zur Herstellung reiner Verbindungen können Chemiker je nach
dem gewünschten Reinheitsgrad auf eine Vielzahl unterschiedlicher
Variablen zurückgreifen. In diesem Whitepaper möchten
wir die Faktoren erläutern, die für eine erfolgreiche Aufreinigung
mithilfe der Flash-Chromatographie kontrolliert werden müssen. Tags: White Papers
Part No: PPS490.gerPublished: 20191.65 MBFormat: pdfDownload
Purification is a fundamental step in drug discovery and, as pioneers of automated flash purification, Biotage is your ideal partner. Our core philosophies of Quality, Reliability and Environmentalism are drawn from our Swedish heritage.
Our smart and intuitive design comes from our knowledge of what our customers need each day. You can see why our customers have “Konfidence” with a capital “K” in our brand.
When it comes to purification there are five reasons to Selekt Biotage.
1. Inspire Productivity
Your efficiency is key for you and is of paramount importance for us. That is why we have designed a compact System with added flexibility in terms of column position and setting up the purification. Customers can choose their desired methodology and keep productivity high at the same time.
2. Finer Control
When performing challenging syntheses, you need results that are fast and reliable. Our new advanced flash purification system utilizes the most sophisticated technology to simplify even the most advanced chemistry.
3. Unbelievably Easy to Use
The Selekt system is flexible enough for both novices and experts, and our experience supports you every step of the way. A beautiful graphical user interface presented on a large touchscreen enables even the most complex tasks to become simplicity itself. We also brought in some colors to make it more fun, so you’ll enjoy doing purifications with us!
4. Amazing Reliability
Not only do your results have to be reliable, but your instruments too! We take care of everything to remove every hassle from your daily job and let you focus on what is really important for you. You can rely on Biotage in every aspect as your preferred partner in Flash purification.
5. The Greenest System
Our new purification system enables you to to reduce waste to a minimum if you combine Selekt with our new Biotage® Sfär columns. So why not give them a try?