Showing posts written by Biotage
Data reliability in forensic toxicology is of paramount importance. The possibility of false positives and/or false negatives can have wide ranging consequences and impacts decisions on various parts ...
Scope This application note will outline appropriate methods for the extraction of organophosphorus pesticides from ground water as outlined in EPA method 8141B using the Atlantic® C18 SPE disk proces...
Peptide drug discovery programs have advanced to the clinic as the rules for small molecule-like transport and bioavailability have become more thoroughly understood. Macrocyclic peptides, in particul...
The Biotage® Extrahera™ GLP Software is designed to automate sample preparation in many applications that utilize solid-phase extraction (SPE), supported liquid extraction (SLE), dual mode extraction ...
Hair analysis is growing in popularity due to the non-invasive nature of the sample collection. Although not used as routinely as other matrices such as blood or urine it does have advantages in that ...
Introduction Concentrations of Vitamin B1 (Thiamine Diphosphate, TDP) and B6 (Pyridoxal-5-Phosphate, PLP) in whole blood are measured clinically to measure various metabolic functions. Accurate concen...
Peptides are well suited for use as tool compounds to interrogate biological systems and processes due to their chameleonic ability to mimic a potential protein partner within the biological system of...
Introduction Whole blood is often the specimen of choice for detection of drugs in the forensic laboratory. Samples are typically extracted to remove interferences and isolate the analytes of interest...
Figure 1. Structure of Diazepam Introduction This application note describes the extraction of benzodiazepine compounds from whole blood, prior to GC/MS analysis. This protocol also allows the simulta...