Synthesis of long oligonucleotides
Oligonucleotides are short strands of DNA or RNA with wide-ranging applications across biology, chemistry and medicine. The current gold standard method of choice for the chemical synthesis of oligonu...
Literature
Showing posts written by Biotage
Parallel peptide synthesis at elevated temperatures with Syro
This application demonstrates the reproducible multiple peptide synthesis on a Syro parallel peptide synthesizer equipped with Syro heating blocks. Effective heat transfer combined with efficient vort...
Simultaneous extraction of aldosterone and angiotensin I and II from human plasma using EVOLUTE® EXPRESS ABN
For research use only. NOT for use in diagnostic procedures.
Choosing the solid-phase extraction media for synthetic peptide clean-up
Summary Solid phase extraction (SPE) is a commonly used method to clean up various types of samples before analyzing them using LCMS. It is also an effective way to improve the purity of crude synthet...
Extraction and analysis methods for fentanyl and fentanyl analogues in whole blood and urine
Introduction Fentanyl and fentanyl-related analogues have been identified as the root cause of several notable drug overdoses in recent years. The demand for testing of these drugs has rapidly increas...
Reducing evaporative crosstalk in urine assays using 96-well plates
LC-MS/MS analysis of volatile analytes is problematic when 96-well plates are used. Solid phase extraction of urine with high drug concentrations can cause contamination of the elution solvent during ...
Evaluation of novel automated sample preparation compared to manual processing in forensic toxicology
Data reliability in forensic toxicology is of paramount importance. The possibility of false positives and/or false negatives can have wide ranging consequences and impacts decisions on various parts ...