Showing posts written by Biotage
Exposure to per and polyfluoroalkyl substances (PFAS) has been linked with changes in metabolism, increased cholesterol, and high incidence of some forms of cancer. PFAS pose particular challenges in ...
Fentanyl and fentanyl-related analogues have been identified as the root cause of several notable mass-overdose events in recent years. The demand for testing of these drugs has rapidly increased due ...
Summary This application note highlights how simple Gradient Optimization and single vessel product collection – enabled by a collection bed bypass function - minimized solvent use and reduced the num...
This application note will outline optimized methods for the extraction of hormones from water as outlined in EPA Method 539 using Biotage automated or manual SPE solutions. The first section will hig...
Routine testing for drugs of abuse (DOA) in urine is commonly performed by many clinical, forensic, and pain management laboratories. The method of testing varies but can often provide unwanted load s...
Introduction The interest in naturally occurring and designed bioactive cyclic peptides is ever increasing.1–4 Cyclic peptides often have an increased stability against proteolysis compared with linea...
Introduction Reductive amination is a favored chemical reaction in synthesis of organic amines. However, like many synthetic techniques, it can create side reactions and byproducts that require remova...
COVID-19 triggered accelerated research into vaccine development. Some of the vaccines are based on mRNA which, if not protected, easily degrades in humans before its therapeutic benefits can be reali...
Application note scope The purpose of this application note is to outline an automated extraction method utilizing the Atlantic® DVB SPE Disk and the Biotage automated and manual SPE solutions for the...
The ISOLUTE® family of both endcapped and non-endcapped, non-polar, silica based sorbents are used to extract organic compounds from aqueous matrixes.