Showing all posts
We’ve looked at the biology, chemistry and the workflow so let's now get to the heart of the matter for many, the process economics. As we stated previously, we need to embrace the rigors of the comme...
Cannabidiolic acid, or CBDA, has purported analgesic properties relieving pain and inflammation[1]. CBDA is also the starting material for CBD which is produced through a procedure called decarboxylat...
As one of the major cannabinoids present in cannabis, Cannabigerol (CBG), is gaining interest as possible therapeutic. Though all other cannabinoids are created from CBGA (the acid form of CBG), it is...
Cannabidiol or CBN, is a cannabinoid of interest because of its potential in medicinal applications. However, CBN is not expressed by cannabis plants in high yields and is actually formed from degrade...
Previously, I have posted on a normal-phase flash chromatography method to separate and isolate CBG from a CBD-rich hemp distillate. CBG is just one of many naturally occurring minor cannabinoids of i...
Flash chromatography is the go-to cannabinoid purification technique because of its effectiveness and relative ease of use. This technology can easily remove THC from CBD in a process known as THC rem...
Cannabicitran is one of many minor cannabinoids found in cannabis though not much is known about this compound as far as possible medicinal benefits.
Many microwave assisted organic synthesis (MAOS) reactions use polar solvents such as alcohols, DMF, DMSO, because they absorb and transfer microwave energy very efficiently. However, the downside of ...
In past posts I discussed which solvents work best for sample loading in reversed-phase flash chromatography. Recently, I was asked to provide some insight as which solvents are best in normal-phase f...
For chemists preferring or needing to dry load their crude sample mixtures to get an acceptable flash purification result, using the right ratio of sample to sorbent can be quite important. Too much s...