Can organic solvent choice impact reversed phase flash chromatography separations?
This post describes how organic solvent choice impacts reversed phase separations.
When should more than two solvents be used in a flash chromatography method?
This post discusses two situations when the addition of a third solvent in a purification method addresses the issue.
Does C-terminal amino acid affect cyclization efficiency?
Head-to-tail macrocycles remain difficult to synthesize on resin. Here is how C-terminal amino acid affects cyclization efficiency.
How short can I make my flash chromatography method?
This post highlights the time and solvent savings attainable with shorter linear gradients when maintaining gradient slope.
Does peptide length and size affect cyclization efficiency?
Head-to-tail macrocycles remain difficult to synthesize on resin. Here is how the length and size of your pepetide can affect purity and ...
Are step gradients effective with reversed phase flash chromatography?
This post highlights the time savings achievable using a step gradient in reversed phase flash chromatography.
How does an acid pH modifier impact flash chromatography?
This post discusses the pros and cons of adding acid to a flash purification method.
How can I overcome chromatography solvent detection interferences
This post discusses the benefits of UV baseline correction with flash chromatography.
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