Showing posts tagged with "small-molecules-and-synthetic-therapeutics"
Our recent survey of organic synthetic chemists showed that more than half of you feel that the most enjoyable aspect of your work is researching new chemistries, while 33% told us that preparing reac...
Isn’t amazing chemistry what you want to do every day? Don’t you strive for white crystalline final products? But things get in the way, such as other priorities, endless emails and frequent interrupt...
Discovery chemistry labs synthesizing new molecular entities (NMEs) are under pressure to improve their productivity. Optimizing the design-make-test-analyze (DMTA) cycle in the discovery process mean...
Pharmaceutical researchers feel real pressure to increase their R&D productivity by ‘doing more with less’. Despite having limited internal resources and specialized expertise, discovery chemistry res...
New drug substances, the result of more than a decade of pharmaceutical research and development, have revolutionized society by saving lives, increasing life-spans, reducing suffering, avoiding surge...
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I think that the phrase ‘creative productivity’ captures the essence of an organic chemist’s work. It’s not about the number of new molecules produced per day at all. Creative organic chemists have mu...
Organic reactions are generally inefficient, which means that crude reaction mixtures require work-up and purification to remove by-products and unreacted starting materials and/or catalysts. The goal...