Showing posts written by Biotage
Introduction Automated sample preparation using the Biotage® Extrahera™ was compared to an equivalent manual method utilizing a vacuum manifold. A selection of beta blocker drugs were extracted from p...
Dr. Sean P. Bew is Associate Professor in Chemistry at the University of East Anglia, UK, where he specializes in medicinal chemistry, isotope labelling, aziridine chemistry and supramolecular natural...
Introduction The pace of innovation from life science researchers is constantly pushing the limits of available tools. While technologies such as high throughput construct screening, crystallography a...
For research use only. NOT for use in diagnostic procedures. Figure 1. Structures of amphetamine, diazepam, butabarbital and atrazine respectively. Introduction This application note describes the ext...
Introduction Hexane extractable material (HEM), also known as Oil & Grease extraction is a simple water quality measurement. The measurement can be used to assess pollution for compliance or as a meas...
Executive summary Peptides have garnered much attention in a variety of applications over the last few years, and interest only continues to grow. With improved synthetic strategies, peptides are now ...
You analyze a lot of biological samples. You deliver accurate, reliable data, consistently. You use sophisticated, high-end analytical techniques such as LC-MS/MS or GC-MS. And the pressure is always ...
Part I: Principles of evaporation Evaporation is a process used to concentrate samples by vaporizing and removing liquid solvents, leaving behind the dissolved solid components. Evaporation is essenti...
The main purpose of sample preparation is to extract the target analyte(s) from the sample matrix, allowing them to be measured by the chosen analytical technique, such as LC-MS/MS or GC-MS. This can ...
Introduction Discovering new chemical entities (NCEs) or new molecular entities (NMEs) is costly and time consuming. One needs only to look at the top 15 global pharmaceutical companies to see how exp...