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Introduction There are 8 water soluble analogues of vitamin B that are relevant to the metabolic health of the human host. Of particular interest to this study is the determination of vitamin B3, a pr...
Introduction Antiepileptic drugs (AED) are prescribed to suppress seizures in epilepsy patients. A variety of different types of AEDs have been synthesized to pharmacologically address different types...
For research use only. NOT for use in diagnostic procedures. Figure 1. Chemical structures of three common PEth species.
Figure 1. Structures of analytes.
This application note describes the extraction of neutral and zwitterionic antiepileptic drugs fortified in serum and urine using ISOLUTE® SLE+ in a 96-well plate format. Figure 1. Structures of Carba...
Introduction Per- and polyfluoroalkyl substances (PFAS) have been widely manufactured and utilized across numerous industrial and consumer applications since their introduction in the mid-20th century...
Introduction Accurate quantitation of therapeutic oligonucleotides in tissue is essential for pharmacokinetic, toxicology, and broader bioanalytical studies, particularly during clinical development a...
Introduction Accurate quantitation of oligonucleotides in human plasma is essential for pharmacokinetic and bioanalytical studies, particularly during clinical development and therapeutic monitoring. ...
Introduction Breastfeeding offers significant health benefits for both infants and mothers, promoting optimal nutrition, immune protection, and developmental outcomes. However, maternal use of illicit...
Introduction The screening of patient urine samples for basic drugs is typically performed following a lengthy sample preparation methodology that requires a time consuming dry down step. A novel elut...