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This application note describes the extraction of a range of SPICE drugs and metabolites in urine which are typically screened in forensic toxicology panels using ISOLUTE® SLE+ in a 96-well plate form...
Introduction The UV absorption spectrum of some solvents overlaps with the product they dissolve, meaning that fraction collection processes cannot distinguish between solvent and product. Luckily, th...
Scope This application note will outline optimized methods for the extraction of organophosphorus pesticides as outlined in EPA method 1657 using the Atlantic® C18 SPE disk processed using Biotage aut...
This application shows how the β-amyloid (1-42) peptide was successfully synthesized in 0.1 mmol scale on a Biotage® Initiator+ Alstra™ fully automated microwave peptide synthesizer.
Introduction The detection of per- and polyfluoroalkyl substances (PFAS) within our air, water, and soil has confirmed their place as persistent pollutants that pose significant health risks upon huma...
Introduction This application note describes a solid phase extraction (SPE) protocol for the extraction of teicoplanin from plasma prior to HPLC-DAD analysis. Teicoplanin (Figure 1) is a glycopeptide ...
Introduction This procedure is recommended for the extraction of a variety of diuretics from urine using non-polar polymeric SPE. The analyte suite includes thiazides, carbonic anhydrase inhibitors, l...
Introduction Labelled peptides are important tools to study molecular interactions1 and are increasingly utilized with the growing number of peptide-based therapeutics.2 Biological assays frequently r...
Acknowledgements: A very special thank you to Adirondack Environmental Services for working with us on finding a solution for reducing sample volumes for EPA Method 608.3.
Introduction Peptide nucleic acids (PNAs) are DNA mimics where the sugar phosphate backbone of DNA is replaced by a peptide backbone consisting of N-(2-aminoethyl)glycine units. The purine nucleo- bas...