Showing posts tagged with "scale-up"
Whether for pharma, fine chemical, agrochemical, electronic or natural product research, in recent years, there has been increasing pressure to achieve and deliver higher purity products. Chemical pro...
The ALC-0315 lipid (Figure 1) gained worldwide recognition as a component of the SARS-CoV-2 vaccine [BNT162b2, developed by BioNTech and Pfizer]. Today, it is one of several lipid-based components use...
Summary The automated gradient optimization feature in Biotage® Selekt flash purification systems accelerates purification, reduces solvent usage, and maintains loading capacity.
The scale up is based on Kyowa’s extensive experience in process validation and investigational drug GMP manufacturing
Extracting target compounds from large volumes of mixture confronts chemists with challenges which are right at the heart of large scale process chemistry. Ruichao Shen at Satori Pharmaceuticals knows...
When a drug candidate is going to be tested, volumes must be scaled up. This requires scalable solutions for purification. From traditional small molecules to peptides, natural product extraction, or ...
In this interview Mr. Akutagawa, Executive Director and Mr. Oi, Ph.D., Senior Manager of the Kashima Manufacturing and Quality Technology Department at Eisai, share their experiences with the testing ...
Efficiency and reproducibility are critical for successful scale-up. Biotage flash purification solutions are designed for simple and seamless scale up from development to large-scale cGMP manufacturi...
Isolera™ LS 150 is a fully automated flash chromatography system that allows you to bridge the gap between lab scale and production. Designed to adapt to your evolving needs, it ensures reproducibilit...
Compliance with GMP is a necessary condition for drug authorization however the scrutiny that it demands can pose local engineering and chemistry issues because process chemists are under increasing p...