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Biotage® Sfär

Sfär for Spherical, Biotage for Quality

Sfär1
Sfär6 Sfär5 Sfär4 Sfär3 Sfär2 _MG_2155 IMG2148 _MG_2144

Sfär is the Swedish word for "sphere", and the name of our columns reflects the fact that we have  made spherical silica a standard due to its higher surface area and higher loading capacity. Reliable and flexible, Biotage® Sfär columns deliver larger loading capacities, tighter elution bands and purer fractions than traditional flash columns.

Biotage developed and introduced pre-packed columns for flash purification in 1994. Today our broad selection of columns enables professionals to choose the solution which best suits their purification needs. Biotage® Sfär is a complete portfolio of flash columns, available in a large variety of sizes from 5 g to 350 g and in a range of media types, so you can purify milligrams to multi-grams of your valuable compounds quickly and easily.

The Greenest Columns

Chemistry, by its very nature, involves the use of chemicals that can be harmful, toxic and potentially damaging to the environment. Drug discovery currently has a large and expensive environmental footprint so finding a solution is good for both the chemist and the environment. Our contribution to protect the environment with the new columns is clear.

Purify More With Less

A first step to a greener purification is using a column with a higher loading capacity, so you can purify the same amount of sample on a smaller column  and hence use lower flow rates and less solvent;  and ultimately finish the job quicker. This will make your whole process greener, less expensive and also more efficient.

To do that you need a column that has been designed with your needs in mind by the pioneers in flash purification: Biotage® Sfär HC (High Capacity).

Double Your Loading Capacity

Our proprietary silica in Sfär HC delivers  increased surface area, no fines, and remarkably low pressure. This means your loading capacity is much higher compared to standard columns, thus reducing purification costs, environmental impact, and making separation faster.

Sfär columns have been designed to tolerate higher pressures, so you can use higher flows to speed up the purification process even further.

The unique design of Biotage® Sfär makes it possible to load your columns in seven different ways, including three different dry loading options thanks to the Biotage Samplet®. For your difficult separations, when you want to utilize dry loading in the most convenient way, take advantage of the orange flower shaped cap of Biotage® Sfär D (Duo).

The Most Flexible Columns

With Biotage® Sfär D we are introducing additional flexibility in the way columns can be loaded.

Liquid Loading

  • By pushing the sample into the top port of the column with a syringe
  • By unscrewing the top, removing the spacer, and pouring the sample on to the top of the stationary phase

Loading Biotage® Sfär16Loading Biotage® Sfär15

Dry Loading

  • By absorbing your sample onto silica, drying, and then introducing the doped silica into the top cavity of the column
  • By absorbing your sample onto another sorbent of your choice before introducing to the column cavity
  • By introducing your sample to a Samplet® unique to Biotage®, evaporating the solvent, and then loading the samplet into the column cavity – a simple and effective way of loading your sample on to silica container
  • By taking an empty Samplet® and filling it with your own specialist loading matrices prior to doping with your sample

Loading Biotage® Sfär01Loading Biotage® Sfär28

The spherical particles in the columns support faster flow rates to speed purification and improve productivity.

When used with Biotage® Selekt, flash purification system the instrument will suggest the optimal cartridge for your conditions and will help you in optimizing the utilization of Sfär columns.

CONSUMABLES

Part No. Description Product type Pack Size Price
FSAD-0454-0005 FSAD-0454-0005 Biotage® Sfär Amino D ­ Duo 50 µm 5 g Consumables 20 Log in for price
FSAD-0454-0011 FSAD-0454-0011 Biotage® Sfär Amino D ­ Duo 50 µm 11 g Consumables 20 Log in for price
FSAD-0454-0028 FSAD-0454-0028 Biotage® Sfär Amino D ­ Duo 50 µm 28 g Consumables 20 Log in for price
FSAD-0454-0055 FSAD-0454-0055 Biotage® Sfär Amino D ­ Duo 50 µm 55 g Consumables 10 Log in for price
FSAD-0454-0110 FSAD-0454-0110 Biotage® Sfär Amino D ­ Duo 50 µm 110 g Consumables 10 Log in for price
FSAD-0454-0220 FSAD-0454-0220 Biotage® Sfär Amino D ­ Duo 50 µm 220 g Consumables 4 Log in for price
FSAD-0454-0380 FSAD-0454-0380 Biotage® Sfär Amino D ­ Duo 50 µm 380 g Consumables 4 Log in for price
FSBD-0411-0010 FSBD-0411-0010 Biotage® Sfär Bio C18 D ­ Duo 300 Å 20 µm 10 g Consumables 2 Log in for price
FSBD-0411-0025 FSBD-0411-0025 Biotage® Sfär Bio C18 D ­ Duo 300 Å 20 µm 25 g Consumables 2 Log in for price
FSBD-0411-0050 FSBD-0411-0050 Biotage® Sfär Bio C18 D ­ Duo 300 Å 20 µm 50 g Consumables 2 Log in for price
FSBD-0411-0100 FSBD-0411-0100 Biotage® Sfär Bio C18 D ­ Duo 300 Å 20 µm 100 g Consumables 2 Log in for price
FSBD-0412-0010 Biotage® Sfär Bio C4 D ­ Duo 300 Å 20 µm 5 g Consumables 2 Log in for price
FSBD-0412-0025 FSBD-0412-0025 Biotage® Sfär Bio C4 D ­ Duo 300 Å 20 µm 10 g Consumables 2 Log in for price
FSBD-0412-0050 FSBD-0412-0050 Biotage® Sfär Bio C4 D ­ Duo 300 Å 20 µm 25 g Consumables 2 Log in for price
FSBD-0412-0100 FSBD-0412-0100 Biotage® Sfär Bio C4 D ­ Duo 300 Å 20 µm 50 g Consumables 2 Log in for price
FSRD-0445-0005 FSRD-0445-0005 Biotage® Sfär Silica D ­ Duo 60 µm 5 g Consumables 20 Log in for price
FSRD-0445-0010 FSRD-0445-0010 Biotage® Sfär Silica D ­ Duo 60 µm 10 g Consumables 20 Log in for price
FSRD-0445-0025 FSRD-0445-0025 Biotage® Sfär Silica D ­ Duo 60 µm 25 g Consumables 20 Log in for price
FSRD-0445-0050 FSRD-0445-0050 Biotage® Sfär Silica D ­ Duo 60 µm 50 g Consumables 10 Log in for price
FSRD-0445-0100 FSRD-0445-0100 Biotage® Sfär Silica D ­ Duo 60 µm 100 g Consumables 10 Log in for price
FSRD-0445-0200 FSRD-0445-0200 Biotage® Sfär Silica D ­ Duo 60 µm 200 g Consumables 4 Log in for price
FSRD-0445-0350 FSRD-0445-0350 Biotage® Sfär Silica D ­ Duo 60 µm 350 g Consumables 4 Log in for price
FSRS-0445-0005 Biotage® Sfär Silica ­ 60 µm 5 g Consumables 20 Log in for price
FSRS-0445-0010 FSRS-0445-0010 Biotage® Sfär Silica ­ 60 µm 10 g Consumables 20 Log in for price
FSRS-0445-0025 Biotage® Sfär Silica ­ 60 µm 25 g Consumables 20 Log in for price
FSRS-0445-0050 FSRS-0445-0050 Biotage® Sfär Silica ­ 60 µm 50 g Consumables 10 Log in for price
FSRS-0445-0100 Biotage® Sfär Silica ­ 60 µm 100 g Consumables 10 Log in for price
FSRS-0445-0200 FSRS-0445-0200 Biotage® Sfär Silica ­ 60 µm 200 g Consumables 4 Log in for price
FSRS-0445-0350 FSRS-0445-0350 Biotage® Sfär Silica ­ 60 µm 350 g Consumables 4 Log in for price
FSUD-0401-0006 FSUD-0401-0006 Biotage® Sfär C18 D ­ Duo 100 Å 30 µm 6 g Consumables 2 Log in for price
FSUD-0401-0012 Biotage® Sfär C18 D ­ Duo 100 Å 30 µm 12 g Consumables 2 Log in for price
FSUD-0401-0030 FSUD-0401-0030 Biotage® Sfär C18 D ­ Duo 100 Å 30 µm 30 g Consumables 2 Log in for price
FSUD-0401-0060 FSUD-0401-0060 Biotage® Sfär C18 D ­ Duo 100 Å 30 µm 60 g Consumables 2 Log in for price
FSUD-0401-0120 FSUD-0401-0120 Biotage® Sfär C18 D ­ Duo 100 Å 30 µm 120 g Consumables 2 Log in for price
FSUD-0401-0240 FSUD-0401-0240 Biotage® Sfär C18 D ­ Duo 100 Å 30 µm 240 g Consumables 1 Log in for price
FSUD-0401-0400 FSUD-0401-0400 Biotage® Sfär C18 D ­ Duo 100 Å 30 µm 400 g Consumables 1 Log in for price
FSUD-0443-0005 FSUD-0443-0005 Biotage® Sfär Silica HC D ­ High Capacity Duo 20 µm 5 g Consumables 20 Log in for price
FSUD-0443-0010 Biotage® Sfär Silica HC D ­ High Capacity Duo 20 µm 10 g Consumables 20 Log in for price
FSUD-0443-0025 FSUD-0443-0025 Biotage® Sfär Silica HC D ­ High Capacity Duo 20 µm 25 g Consumables 20 Log in for price
FSUD-0443-0050 FSUD-0443-0050 Biotage® Sfär Silica HC D ­ High Capacity Duo 20 µm 50 g Consumables 10 Log in for price
FSUD-0443-0100 FSUD-0443-0100 Biotage® Sfär Silica HC D ­ High Capacity Duo 20 µm 100 g Consumables 10 Log in for price
FSUD-0443-0200 FSUD-0443-0200 Biotage® Sfär Silica HC D ­ High Capacity Duo 20 µm 200 g Consumables 4 Log in for price
FSUD-0443-0350 FSUD-0443-0350 Biotage® Sfär Silica HC D ­ High Capacity Duo 20 µm 350 g Consumables 4 Log in for price
FSUS-0443-0005 Biotage® Sfär Silica HC ­ High Capacity 20 µm 5 g Consumables 20 Log in for price
FSUS-0443-0010 FSUS-0443-0010 Biotage® Sfär Silica HC ­ High Capacity 20 µm 10 g Consumables 20 Log in for price
FSUS-0443-0025 Biotage® Sfär Silica HC ­ High Capacity 20 µm 25 g Consumables 20 Log in for price
FSUS-0443-0050 FSUS-0443-0050 Biotage® Sfär Silica HC ­ High Capacity 20 µm 50 g Consumables 10 Log in for price
FSUS-0443-0100 Biotage® Sfär Silica HC ­ High Capacity 20 µm 100 g Consumables 10 Log in for price
FSUS-0443-0200 FSUS-0443-0200 Biotage® Sfär Silica HC ­ High Capacity 20 µm 200 g Consumables 4 Log in for price
FSUS-0443-0350 Biotage® Sfär Silica HC ­ High Capacity 20 µm 350 g Consumables 4 Log in for price