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Small Molecules and Synthetic Therapeutics

This post discusses the reversed-phase purification of highly lipohilic compounds using high organic content mobile phases.

Small Molecules and Synthetic Therapeutics

The stationary phase properties directly impacts your purification. Read more to learn about using large-pored particles for improved ...

Small Molecules and Synthetic Therapeutics

This post discussed the impact of media pore size on small-molecule flash column chromatography.

Small Molecules and Synthetic Therapeutics

This posts describes tips to improve reversed-phase method development.

Small Molecules and Synthetic Therapeutics

When should I add acid to my detector make-up solvent when using mass-directed flash chromatography?

Small Molecules and Synthetic Therapeutics

This post discusses the benefits of spending only 10 minutes developing TLC data to support optimized flash chromatography.

Small Molecules and Synthetic Therapeutics

Does high performance flash column chromatography require high performance TLC for method development?

Small Molecules and Synthetic Therapeutics

Does mass detection make-up solvent choice matter?

Small Molecules and Synthetic Therapeutics

This post discusses the best options for creating and transferring HPLC-based methods to flash chromatography.

Small Molecules and Synthetic Therapeutics

This post discusses the benefits of acetone over ethyl acetate in normal-phase flash chromatography.