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Using adducts and fragments to identify compounds in mass-directed flash chromatography
Small Molecules and Synthetic Therapeutics
This post discusses how to use adducts and fragments to identify compounds in mass-directed flash chromatography.
What impact do buffers have on APCI mass detection?
Small Molecules and Synthetic Therapeutics
This post describes the impact buffers and acids have on APCI mass detection.
Packing a column is part science and part art...and Biotage has both
Small Molecules and Synthetic Therapeutics
The clip shows the long history in Biotage column chromatography.
Which dry load sorbent should I use for flash column chromatography?
Small Molecules and Synthetic Therapeutics
When dry loading with flash chromatography, the sorbent choice can impact compound purification effectiveness.
The three reasons you should be using step gradients for flash column chromatography
Small Molecules and Synthetic Therapeutics
Step gradient flash chromatography improves loading capacity, while reducing solvent use and overall purification time.
Greener flash chromatography tips
Small Molecules and Synthetic Therapeutics
Green flash chromatography is achievable and inexpensive. Using columns packed with small, high surface area silica is the simplest way to ...
Dry loading media options – diatomaceous earth
Small Molecules and Synthetic Therapeutics
Diatomaceous earth is an excellent media for dry loading in both normal- and reversed-phase flash chromatography.
How many ways can you load sample on your column?
Small Molecules and Synthetic Therapeutics
Dry loading can give better results in chromatography sometimes compared to liquid loading. Read more!
A Workflow for Academic Drug Discovery - Baylor University Customer Case
Small Molecules and Synthetic Therapeutics
This article discusses the impact of introducing the Biotage Organic Workflow into a university laboratory via an interview with Director ...
How to minimize particulate build-up in flash chromatography systems
Small Molecules and Synthetic Therapeutics
Sometimes during flash chromatography the system will overpressure due to a flow blockage. This post provides some tips to prevent this ...
