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Vitamin D deficiency can result in various health issues such as osteoporosis, liver and kidney problems and is associated with increased risk of cancers and multiple sclerosis. From this standpoint v...
This poster compares sample preparation options for the extraction of a panel of endogenous steroids from serum. LC-MS/MS parameters were investigated for increased sensitivity: MRM transitions, chrom...
Dilute and shoot (D/S) is the most common form of sample preparation for the high throughput analysis of drugs of abuse (DoA) in urine. Although superior in extract cleanliness, solid phase extraction...
Drugs of abuse (DOA) testing is vital for many clinical, forensic, and pain management laboratories One hindrance with common testing methods is that patient samples are not always available in high q...
The ability to extract a broad range of different drugs from a biological matrix allows for the expedited analysis of a patient sample using LCMS- MS. Typically small molecules are extracted from matr...
US EPA method 625 is used to determine acidic, basic, and neutral semi-volatile organic compounds (SVOC) in municipal and industrial wastewater. Revision A of this method is applied to a total possibl...
In medicinal chemistry each intermediate and final product needs purification. Historically, the primary tool for reaction purification has been normal-phase flash chromatography sometimes followed by...
Evaporative crosstalk is well-to-well cross contamination during extract evaporation after SLE or SPE extraction in a 96 well plate. It is often observed with volatile analytes like methamphetamine an...
The opioid crisis in the United States has necessitated monitoring of these drugs in biological fluids by many state health laboratories. Urine is a common matrix for analysis, and labs require a simp...
Traditionally, peptide purification has relied on preparative high performance liquid chromatography (prep-HPLC), known for its excellent resolution and impurity removal. However, this method is often...