Literature

Introduction Tobacco-specific nitrosamines, TSNAs, are carcinogens found in tobacco products, including e-cigarettes and smokeless tobacco. NNN (n-nitrosonornicotine), NNK (4-(methylnitrosamino)-1-(3-...

Scope The purpose of this application note is to outline an automated extraction method utilizing the Atlantic® HLB SPE Disk and the Biotage automated and manual SPE solutions for the extraction of ho...

This application note describes the extraction of a range of SPICE drugs and metabolites in urine which are typically screened in forensic toxicology panels using ISOLUTE® SLE+ in a 96-well plate form...

Introduction The UV absorption spectrum of some solvents overlaps with the product they dissolve, meaning that fraction collection processes cannot distinguish between solvent and product. Luckily, th...

Scope This application note will outline optimized methods for the extraction of organophosphorus pesticides as outlined in EPA method 1657 using the Atlantic® C18 SPE disk processed using Biotage aut...

This application shows how the β-amyloid (1-42) peptide was successfully synthesized in 0.1 mmol scale on a Biotage® Initiator+ Alstra™ fully automated microwave peptide synthesizer.

Introduction This application note describes a solid phase extraction (SPE) protocol for the extraction of teicoplanin from plasma prior to HPLC-DAD analysis. Teicoplanin (Figure 1) is a glycopeptide ...

Introduction This procedure is recommended for the extraction of a variety of diuretics from urine using non-polar polymeric SPE. The analyte suite includes thiazides, carbonic anhydrase inhibitors, l...

Introduction Labelled peptides are important tools to study molecular interactions1 and are increasingly utilized with the growing number of peptide-based therapeutics.2 Biological assays frequently r...