Showing posts tagged with "application-note"
This application note describes the use of ISOLUTE® HM-N as a support material for pre-adsorption of a reaction mixture prior to flash chromatography. This approach is useful when loading reaction mix...
Whether for pharma, fine chemical, agrochemical, electronic or natural product research, in recent years, there has been increasing pressure to achieve and deliver higher purity products. Chemical pro...
Introduction Axitinib (Figure 1) is a type of molecularly targeted drug used in renal cell carcinoma. To avoid serious side effects and achieve maximal therapeutic efficacy, it is crucial to determine...
The ALC-0315 lipid (Figure 1) gained worldwide recognition as a component of the SARS-CoV-2 vaccine [BNT162b2, developed by BioNTech and Pfizer]. Today, it is one of several lipid-based components use...
Introduction Flash chromatography has evolved from manual techniques using silica pads and glass columns to automated systems with prepacked silica columns. This shift has significantly improved purif...
Scope This application note will outline methods for the extraction of nonyl phenol and bisphenol A using Biotage automated or manual SPE solutions and the DryVap® Concentrator System. The first secti...
Introduction Per- and polyfluoroalkyl substances (PFAS) have been extensively produced and applied across industrial and consumer sectors for decades, resulting in their designation as a priority clas...
Introduction Per- and polyfluorinated alkyl substances (PFAS) have been used abundantly since their inception in the twentieth century and have become a closely monitored class of compounds within env...
Clean plasmid DNA preparations are fundamental for many downstream applications in life science workflows. Processes such as transient transfection for production of antibodies and AAV production, gen...
Summary This application note highlights how simple Gradient Optimization and single vessel product collection – enabled by a collection bed bypass function - minimized solvent use and reduced the num...