Showing posts tagged with "application-note"
Introduction This application note describes the extraction of a suite of NBOMe designer drugs from oral fluid matrix with analysis by laser diode thermal desorption (LDTD)-MS/MS. NBOMes (Figure 1) ar...
Introduction Toxicology screening for tetrahydrocannabinol and its metabolites is routinely conducted in various biological matrices. Whole blood (post mortem or ante mortem) is considered one of the ...
Introduction Immunosuppressant drugs are instrumental in preventing organ and tissue rejection in patients undergoing transplant surgery. Mycophenolic Acid is a common immunosuppressant drug used in p...
Figure 1. Molecular structures of selected analytes
A branched peptidoglycan mimic and a tetra-branched antimicrobial peptide analogue were synthesized on a lysine scaffold using Biotage® Initiator+ Alstra™ microwave peptide synthesizer. These peptide ...
This application note outlines the extraction of five organophosphate compounds monocrotophos, diazinon, malathion, EPN, and methamidophos using one solid phase extraction method with one pre-treatmen...
Introduction Flash chromatography using elution gradients of dichloro- methane and methanol (DCM/MeOH) are the go-to purification technique for chemists trying to purify polar compound mixtures. Howev...
Summary Purification of synthetic peptides represents the largest bottleneck of the entire peptide workflow. Reversed-phase flash chromatography is gaining traction as a strategy to reduce this bottle...
Figure 1. Structure of Amphetamine and Ethylone Introduction This application note describes the extraction of a range of amphetamine-type compounds from whole blood, prior to GC/MS analysis. A protoc...