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The isoelectric point (pI) is a physical property of every peptide (and any other compound for that matter) that can be the root cause for many of the issues experienced when handling these compounds....
Analytical laboratories using techniques such as LC-MS/MS or GC-MS are continuously searching for ways to increase throughput, reduce turnaround times and lower costs. Sample prep is often an underest...
Meeting throughput- and efficiency targets in the analytical laboratory working in a Good Laboratory Practices (GLP) environment involves a constant hunt for new ways to improve workflows and sample q...
Do you have a small to medium size analytical lab and are reaching the limit of what you can achieve with manual sample prep? Perhaps you need more robust sample prep with higher efficiency, less hand...
We’ve all heard about Synthetic Opioids and how frequently they’re being abused, creating an Opioid Epidemic. What many of us aren’t hearing about are other synthetic compounds that are out there. Syn...
Novel Psychoactive Substances (NPSs) are drugs that have been made to have similar effects to common drugs of abuse. For example, synthetic opioids like fentanyl were created to make the user think th...
Confused about how to choose the right sample preparation technique for your compound? Don't know if Solid Phase Extraction (SPE) or Supported Liquid Extraction (SLE) would be best for your sample pre...
Understanding the chemical properties of the compounds in your sample matrix, both the ones you want to detect and the ones you want to eliminate, is necessary for successful method development. Is th...
Urine hydrolysis is a part of sample preparation that we do to eliminate glucuronides before urine analysis. So first, what are glucuronides? And why do we want to get rid of them? In this post, I’ll ...
One of the key features of the so called "in-well hydrolysis" is that it can be a time saver for high throughput labs, which makes it look very appealing. In this blog post, I will be discussing some ...