Literature
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Why evaporation matters: Practical considerations for drugs of abuse and cannabis workflows
Introduction Sample preparation plays a critical role in drugs of abuse (DoA) and cannabis testing workflows. Due to the complex nature of biological matrices, such as whole blood, urine, oral fluid, ...
Preparing the Biotage® Extrahera™ for PFAS analysis: Cleaning procedure
The accurate detection and measurement of per- and polyfluoroalkyl substances (PFAS) is a key focus for environmental, biological, and food samples analytical laboratories. To ensure reliable PFAS qua...
Extraction of THC isomers and metabolites from whole blood
Introduction Analysis of tetrahydrocannabinol (THC) and its isomers is crucial for understanding their pharmacological effects and legal implications of cannabis use, especially in clinical testing, f...
From peptide design to purified therapeutics in 48 hours
Dr Diego Núñez Villanueva is a Tenured Scientist at the Institute of Medicinal Chemistry of the Spanish National Research Council (IQM‑CSIC). Prior to this, he spent several years in the UK, working a...
Extraction of mycotoxins from grain using ISOLUTE® Myco
Introduction Mycotoxins are toxic metabolites produced by fungal molds on food crops. Regulation and legislation for testing of mycotoxin contamination have established which mycotoxins are prevalent ...
Evaluating sustainable ion-pairing agents in peptide chromatography
In peptide purification, mobile-phase acidity (available solution protons) strongly influences peptide charge-state distribution, retention, and separation selectivity. Trifluoroacetic acid (TFA) is w...
Benchmarking Biotage® Rening silica against commercial alternatives for normal-phase flash separations
Introduction Flash chromatography remains a cornerstone purification technique across pharmaceutical, academic, and industrial chemistry workflows due to its speed, scalability, and robustness.1 Perfo...
High-throughput, automated large-scale plasmid purification: Eliminating manual bottlenecks in the therapeutic pipeline
The rapid expansion of biologics discovery – from high-throughput antibody screening to the development of viral vectors for gene therapy – has created an unprecedented demand for high-quality, transf...