Showing posts written by Biotage
Introduction The process of drug discovery over the last 50 years has seen momentous change1. In the 1950’s, lead molecules were found largely by serendipity through in vivo screening of the chemical ...
ALC-0315 attracted global attention as a lipid component of the SARS-CoV-2 vaccine [BNT162b2, from BioNTech and Pfizer]. Lipids stabilize and increase the useful bioavailability of the mRNA therapies....
ISOLUTE® SAX and PE-AX, the strong anion exchangers, are quaternary amines and therefore have a permanent positive charge under all pH conditions. Since this amine is tethered to the silica surface th...
Biotage C18 PhyTip® column benefits Bind a Wide Range of Sizes of Protein/Peptide Sizes Exhibit a High Absolute Binding Capacity Process Results in Low Loss of Peptide Sample Compatible with many comm...
This technical note provides a detailed procedure for the preperation of PFAS compouds according to UCMR 5.
Introduction This application note describes the use of the Biotage® VacMaster™ Disk to extract n-hexane-extractable material (HEM) from wastewaters per EPA Method 1664B. The procedure outlined in thi...
Figure 1. Structural formulae of carbapenem antimicrobials. Introduction Meropenem and Doripenem (Figure 1) are carbapenem antimicrobials that inhibit bacterial cell-wall synthesis and have bactericid...
This technical note provides a detailed procedure for preparing PFAS compounds according to US EPA method 533.
Application note scope The purpose of this application note is to outline an automated extraction method utilizing the Atlantic® C18-HC SPE Disk and the Biotage automated and manual SPE solutions for ...
For research use only. NOT for use in diagnostic procedures. Figure 1. Structures of norepinephrine, epinephrine, dopamine, normetanephrine, metanephrine, and 3-methoxytyramine. Introduction This appl...