Showing posts written by Biotage
Achieving desired sensitivity of plasma catecholamines by LCMS/MS can be problematic. Low LOQs can require a highly sensitive MS instrument. Evaporation of the extracted sample can result in losses du...
Methylisothiazolinone (MI) is an antimicrobial preservative that is used in a variety of personal care products, such as sunscreens, lotions, cosmetics. MI is a cytotoxin and as a result there is conc...
Protein precipitation is a routinely used, high throughput sample preparation technique for removal of protein from biological fluid (plasma, serum or blood) samples prior to analysis by LC-MS/MS. His...
Hair analysis is growing in popularity due to the non-invasive nature of the sample collection. Although not used as routinely as other matrices such as blood or urine it does have advantages in that ...
Solid-phase extraction (SPE) is a powerful technique for rapid, selective sample preparation. Sample preparation prior to analysis is as important to the success of an assay as the analytical techniqu...
For research use only. NOT for use in diagnostic procedures.
This application note describes a method of extraction for metanephrine and normetanephrine from pooled plasma using EVOLUTE® EXPRESS WCX 96-well SPE plates. Figure 1. Structures metanephrine and norm...
Introduction The rapidly growing field of antibody and protein engineering continues to create the demand for technologies that increase the productivity and throughput of protein interaction analysis...
Summary The automated gradient optimization feature in Biotage® Selekt flash purification systems accelerates purification, reduces solvent usage, and maintains loading capacity.
Introduction There are a wide range of volatile and semi-volatile contaminants finding their way into both terrestrial bodies and water sources worldwide. In the United States (US), the contaminants a...