Literature

Routine testing for drugs of abuse (DOA) in urine is commonly performed by many clinical, forensic, and pain management laboratories. The method of testing varies but can often provide unwanted load s...

The ISOLUTE® family of both endcapped and non-endcapped, non-polar, silica based sorbents are used to extract organic compounds from aqueous matrixes.

This application note describes the extraction of sirolimus, tacrolimus, everolimus, cyclosporin A from whole blood samples using supported liquid extraction prior to LC-MS/MS analysis.

Introduction Synthetic benzodiazepines are becoming more abused and are considered “legal highs”. Many forensic laboratories are finding more and more of these compounds in post-mortem and impairment ...

Figure 1: Structural formula of mycophenolic acid. Introduction Mycophenolic acid (Figure 1) is an active metabolite produced by the hydrolysis of the immunosuppressive agent Mycophenolate Mofetil in ...

The ISOLUTE® family of cation exchange sorbents are used to extract organic cations (basic compounds capable of exhibiting a positive charge) from both aqueous and non-aqueous matrixes. Although extra...

Hydroxychloroquine (HCQ) and chloroquine (CQ) are common antimalarial drugs with long half-lives. They are currently being tested as potential treatments for COVID-19. Due to their high publicity in t...

Clinical analysis encompasses a wide range of analytes, whether they are endogenous compounds such as amino acids, vitamins, and hormones or exogenous compounds ("xenobiotics"), such as prescribed and...

Breast feeding is beneficial in meeting the nutritional and immunological needs of infants. Using illegal drugs while breast feeding can have severe consequences for both infant and mother. At Biotage...

This technical note describes the extraction of acidic drugs from biological fluids using ISOLUTE® HAX mixed-mode SPE products.