|Chemical description||Octyl (C8, non-endcapped) and carboxylic acid (COO-)|
|Average particle size||50 µm|
|Pore diameter||60 Å|
This method describes the extraction of quaternary amines, strongly basic amines and amines that are unstable at high pH levels, from biological fluids. The mechanism is mixedmode
hydrophobic and weak cation exchange, allowing acidic elution conditions.
Tags: Application Notes, Biological fluids, Clinical, Quaternary Amines
In this catalog product information is displayed with easy-to-follow application details and supporting documentation.
Ordering information is found following each product listing.
The first decision that needs to be made is what the final analysis will be for the analyte. This will have an impact on the sample and cartridge size, as well as the final elution solvent. Gas chromatography offers higher sensitivity than HPLC, while HPLC is better suited for ionisable species and very high molecular weights. If LC-MS is available, minimal sample clean-up may be required.
Tags: Manuals & User Guides
The ISOLUTE® HCX-Q SPE sorbent has been developed for the extraction of quaternary amines and polybasic
drugs from biological fluids, giving high reproducible recoveries and clean extracts.
Tags: Product Notes
The use of ISOLUTE HCX mixed-mode sorbents is widely accepted for providing high purity extracts of basic drugs from biological fluids. The ISOLUTE HCX-Q sorbent utilizes a combination of weak cation exchange and C8 non-polar retention mechanisms.
Tags: Product Notes
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What is the maximum capacity of an SPE column?
The capacity of a sorbent is defined as the total mass of strongly retained analyte that can be retained by a given mass of the sorbent under optimum conditions.
For most sorbents, this can range from 1-5% by weight. 100 mg of sorbent might retain 1-5 mg of analyte.
Ion exchange sorbents typically have a capacity of 0.3-1 meq/g.Browse more questions and answers >
|Part No.||Description||Product type||Pack Size||Price|
|986-0002-A||ISOLUTE HCX-Q 25 mg/1 mL||Consumables||100||Log in for price|
|986-0005-A||ISOLUTE HCX-Q 50 mg/1 mL||Consumables||100||Log in for price|
|986-0010-A||ISOLUTE HCX-Q 100 mg/1 mL||Consumables||100||Log in for price|
|986-0025-P01||ISOLUTE-96 HCX-Q 25 mg plate||Consumables||1||Log in for price|
|986-0100-P01||ISOLUTE-96 HCX-Q 100 mg plate||Consumables||1||Log in for price|