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Cannabidiol or CBN, is a cannabinoid of interest because of its potential in medicinal applications. However, CBN is not expressed by cannabis plants in high yields and is actually formed from degrade...

Previously, I have posted on a normal-phase flash chromatography method to separate and isolate CBG from a CBD-rich hemp distillate. CBG is just one of many naturally occurring minor cannabinoids of i...

Flash chromatography is the go-to cannabinoid purification technique because of its effectiveness and relative ease of use. This technology can easily remove THC from CBD in a process known as THC rem...

Cannabicitran is one of many minor cannabinoids found in cannabis though not much is known about this compound as far as possible medicinal benefits.

Many microwave assisted organic synthesis (MAOS) reactions use polar solvents such as alcohols, DMF, DMSO, because they absorb and transfer microwave energy very efficiently. However, the downside of ...

In past posts I discussed which solvents work best for sample loading in reversed-phase flash chromatography. Recently, I was asked to provide some insight as which solvents are best in normal-phase f...

For chemists preferring or needing to dry load their crude sample mixtures to get an acceptable flash purification result, using the right ratio of sample to sorbent can be quite important. Too much s...

Flash chromatography is a standard part of an organic chemist’s workflow. It is utilized after most reaction steps in order to remove most of the generated by-products and excess reagents.

Varying the concentrations of mobile phase solvents during flash purification chromatography enhances the ability of the technique to effectively isolate the desired compound from reaction by-products...

When it comes time to purify your reaction mixture or natural product extract, you have a choice to make. Should you simply load your dissolved sample onto your flash column or take the extra step to ...