Walk-up, Walk away Evaporation System
Getting rid of solvent has long been a bottleneck in organic workflow. With the powerful Biotage® V-10 Touch evaporator, those days are gone. This system can evaporate DMSO and NMP with ease, meaning ...
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Let your worries evaporate...it's never been so easy!
Have you heard about Biotage® V-10 Touch? If you're struggling with rapidly drying samples dissolved in either aqueous or organic solvents, or evaporating HPLC fractions from purification and high boi...
When do I need to use an ELSD with flash chromatography?
Flash chromatography can be complex. Solvent choice, column size, stationary phase, loading technique, gradient method, flow rate, and detection parameters are all variables which factor into flash ch...
How Scalable is Flash Chromatography?
Flash chromatography is the most commonly used purification tool for organic and medicinal chemists whose reaction scales typically range from milligrams to grams. The column size to be used for the p...
Can maximizing product yield and purity from messy reaction mixture be green?
Chemical reactions gone wrong, I’m sure we all have experienced this issue, I know I have. You add your reagents in the proper amounts with a suitable solvent and perform your reaction only to find yo...
Can Reaction Temperature Impact Synthetic Product Yield and Purity?
Though this is a purification blog I do, from time to time, like to address synthetic chemistry experimentation findings in the desire to assist you with your reactions, as this is the front-end of yo...
How Can I Speed-up My Synthesis Workflow?
Wouldn’t it be nice if your reactions only created your desired product? Of course the answer is yes, but that is not the reality of synthetic chemistry. Because our chemical reactions yield multiple ...
Organic Chemistry Workflow – Typical Steps and Equipment
Synthetic organic chemistry is the genesis of new pharmaceutical and commercial chemical products. In short, it is based on the idea that two or more carbon-based compounds can be forced to react usin...
How best to extract reaction products from high boiling solvents
Organic chemistry syntheses often use polar, high boiling point solvents to facilitate high temperature reactions. However, these solvents also can complicate down-stream compound purification, either...
Can water be used as an organic synthesis solvent?
The issue of greener synthesis workflow is becoming more important as chemists, and the institutions that employ them, evaluate various ways to reduce organic solvent use in both synthetic and chromat...