Blog
Showing posts tagged with "biologics-and-advanced-therapeutics"
Adeno-associated virus (AAV) purification techniques and challenges
Gene therapy is on the brink of revolutionizing biomedical research and therapeutic sciences, driven by the promise of preventing disease progression and offering long-term cures. While the number of ...
The AAV revolution: A new era in genetic medicine
In recent years, gene therapy has emerged as a ground-breaking approach to tackling various genetic disorders and diseases. By manipulating genetic information using vector-based strategies, researche...
How to choose between affinity tags for protein purification
Finding the right affinity tag can be a challenging task for many. The process requires not only an understanding of your protein but also the downstream process of your purification. You need to find...
Automated pull-down enrichment for biomolecule separation in complex samples
In unconventional assays, it may be difficult to find an effective purification method to separate your biomolecule from your complex sample. With factors such as specificity, selectivity, stability, ...
High-throughput Protein Purification Strategies
Antibodies are indispensable tools that are used in a variety of research applications, diagnostics, and therapeutics. Often, these applications require purified antibodies which means that the antibo...
Perfusion vs. Fed-batch Bioreactors - are there any Differences in Protein Quality?
According to a relatively newly published journal article (Bielser et al. Aug 20 2019, J Biotech), there has been a renewed interest in the science community in perfusion cell culture technologies for...
Protein Expression Analysis - Fast yet Flexible
For anyone looking to automate their protein expression platform, the book “High-Throughput Protein Production and Purification” that was published in July 2019 (ISBN 978-1-4939-9624-7) is an excellen...
Dual Flow Chromatography - Protein Purification in a Pipette Tip
Dual flow chromatography (DFC) is the unique process of performing chromatography separations in a column bed loosely packed at the end of a pipette tip, retained by a minimally absorbing, proprietary...
High Performance Direct and Indirect Immunoprecipitation
Immunoprecipitation is a well-known method in biomedical research for protein isolation. This method is useful to be able to study a protein’s physiochemical properties, post-translational modificatio...