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The diversity of amino acid side chain functionalities, coupled with secondary structure, gives peptides and proteins their unique properties and activities. However, when it comes to chemically synth...
What is the main goal of a peptide chemist? Elizabeth Denton, Ph.D., explains how Biotage sees the peptide synthesis workflow and how we focus on shortening the process time for scientists.
In today’s post I’ll answer the above question by comparing the crude purity of peptides synthesized using amino acid stock solutions or freshly dissolved amino acids.
Synthesizing libraries of peptides - potentially hundreds in a single synthesizer setup - has seen a resurgence of late. These synthetic libraries, often prepared on very small synthesis scales, are r...
Breakthrough during reversed phase purification often occurs for only a couple of reasons: 1) the dissolution solvent is too strong and prevents the compound from fully interacting with the stationary...
Biotage® V-10 Touch rapidly dries samples dissolved in both aqueous and organic solvents. It easily evaporates HPLC fractions from purification, high boiling point solvents from synthesis and features...
Getting rid of solvent has long been a bottleneck in organic workflow. With the powerful Biotage® V-10 Touch evaporator, those days are gone. This system can evaporate DMSO and NMP with ease, meaning ...
Have you heard about Biotage® V-10 Touch? If you're struggling with rapidly drying samples dissolved in either aqueous or organic solvents, or evaporating HPLC fractions from purification and high boi...
Flash chromatography can be complex. Solvent choice, column size, stationary phase, loading technique, gradient method, flow rate, and detection parameters are all variables which factor into flash ch...
Flash chromatography is the most commonly used purification tool for organic and medicinal chemists whose reaction scales typically range from milligrams to grams. The column size to be used for the p...