Fentanyl and its analogs are part of the growing opioid crisis in the United States, and across the world. According to the latest data from the National Survey on Drug Use and Health, more than 2.1 million Americans struggle with an opioid use disorder for either prescription pain relievers or heroin.
Because of this, both routine clinical and post-mortem toxicology testing demands have rapidly increased. Whole blood is a common choice for sample matrix due to its availability, but the viscosity can make blood a challenge to work with. Nowadays, other matrices are also commonly used, like urine, nails and oral fluid.