CLOSE ×
    New Biotage® PhyPrep Maxi Mega Giga
    Endotoxin free Plasmid purification, automated.
    BIOMARK002.426 - Cross Talk SM

    Preventing Cross Talk

    Highlighted Applications

    Avoiding false positive results from sample to sample contamination is critical, and the use of 96-well plates may increase the risk due to close proximity of high concentration samples.

    Evaporating ultra high concentration samples

    Urine specimens analyzed by LC-MS/MS with analyte concentrations in excess of 100,000 ng/mL have been observed in some laboratories. Controlling crosstalk for these samples with such high concentrations presents a special challenge and is particularly difficult for volatile analytes like sympathomimetic amines.

    This poster examines strategies to prevent cross talk for ultra high concentration samples.

    Download

    Avoiding Cross Talk In 96-well Based Sample Preparation

    This guide aims to describe simple practical strategies, hints and tips designed to mitigate or avoid cross-well contamination or ‘cross talk’ in high throughput 96-well based sample preparation techniques.

    Download

    Capture

    Application Note Finder

    Biotage offer a wide range of optimized application notes and our new Application Notes Finder is under construction. In the meantime, don't hesitate to contact us. Our team of application specialists is here to support you!

    Contact Us

    Recommended Products

    ACT
    Biotage® ACT Plate Adapter

    Anti Cross Talk plate adapter is a novel solution to the phenomenon of hot spot cross contamination, or cross talk, during evaporation.

    collection_plate_2_ml_square_pn_121-5203-a
    ISOLUTE® Collection Plates

    Deep Well Collection Plates. A range of square  and round  well collection plates. Constructed from high purity, solvent resistant polypropylene.

    6010010PX01
    SPE Products

    SPE columns, 96-well plates and disks: Polymeric, Non-polar, Polar, Ion exchange, Mixed-mode, Speciality media.

    PPM Manifolds
    Positive Pressure Processing

    Consistent, uniform flow of positive pressure to move both low and high viscosity liquids through plates and columns.

    Extrahera-portrait-side-left_cutout_with_screen
    Extrahera™

    Powerful, user friendly automation system for Supported Liquid Extraction (SLE), Solid Phase Extraction (SPE), Phospholipid Depletion (PLD) and Protein Precipitation (PPT) based methods, in plate or column formats.

    SPE Dry
    96 Well Plate Evaporators

    Designed for high throughput laboratories, to provide efficient solvent evaporation in microplate formats.

    Resources

    Method development chart, tips and tricks and useful insights to optimize your sample prep.

    The pressure is always there to deliver accurate, reliable data, consistently and, if possible, at lower cost.  Sample preparation is critical for  success.

    Smarter Sample Prep: Your workflow from manual processing to automation.

    Make your life easier. Simplify your workflow

    Automated sample preparation reduces errors, improves method robustness and frees up laboratory personnel for other tasks.

    Biotage evaporation systems are designed for fast sample evaporation and minimizing sample handling.

    Discover the full range of sample preparation products from Biotage.