Forensic & Toxicology Sample Preparation

Blood Samples

Highlighted Applications

Blood Sample Prep for GC-MS

If you are using GC-MS for your whole blood analyses, have you thought about updating your sample prep methods? Our application notes describe simple robust procedures - with no need for complicated sample pre-treatment - for many common drug classes:

Amphetamines
Barbiturates
Benzodiazepines
Cocaine and metabolites
Opiates
Propofol
THC

Synthetic Cannabinoids in Whole Blood

Synthetic cannabinoids are sold under a wide range of names such as K2, Spice, Legal Highs. They are synthesized to circumvent existing laws, and new substances are frequently identified. This method for extraction of and clean up of whole blood samples allows for identification of 12 novel synthetic cannabinoids by LC-MS/MS.

Alcohol Biomarkers in Whole Blood

This simple supported liquid extraction method for phosphatidylethanol (PEth) in whole blood does not require complex sample pre-treatment steps, and allows for accurate quantification of 3 common PEth species. The method is fully automatable.

Automated Whole Blood Extraction

Efficient and effective solution for extraction of panel of 49 drugs of abuse from whole blood samples. This application note describes an automated sample preparation procedure which can process 24 samples in approximately 40 mins.

Application Note Finder

Biotage offer a wide range of optimized application notes and our new Application Notes Finder is under construction. In the meantime, don't hesitate to contact us. Our team of application specialists is here to support you!

Recommended Products

ISOLUTE® SLE+

Supported Liquid Extraction plates and columns designed to provide high analyte recoveries, and clean, protein and phospholipid free extracts. Methods are easy to develop, and automation is simple.

BIOMARK002.173 - Vitamin test Evo Express ABN

EVOLUTE® EXPRESS ABN

Excellent sample clean up while enhancing manual or automated sample preparation workflow and delivering reproducible, high sensitivity analytical results. For elution volumes as low as 20 µL.

SPE products

SPE columns, 96-well plates and disks: Polymeric, Non-polar, Polar, Ion exchange, Mixed-mode, Speciality media.

Positive Pressure Processing

Consistent, uniform flow of positive pressure to move both low and high viscosity liquids through plates and columns.

Extrahera™

Powerful, user friendly automation system for Supported Liquid Extraction (SLE), Solid Phase Extraction (SPE), Phospholipid Depletion (PLD) and Protein Precipitation (PPT) based methods, in plate or column formats.

TurboVap® P+

Solvent evaporation of up to 48 samples with independent control of flow in each row. Designed to streamline your workflow following sample processing on a PRESSURE+ 48 unit.

Synthetic Cannabinoids: how to extract them from whole blood?

Among the most widely abused drugs in the world, they are structurally similar and have similar effects to marijuana but are frequently referred to as “legal highs”. How do we analyze for these compounds? How can they be easily extracted from whole blood?

Resources

Get Started with Supported Liquid Extraction

Method development chart, tips and tricks and useful insights to optimize your sample prep.

Avoiding Cross Talk 96-well Based Sample Preparation

Eliminate carryover between samples, and reduce the risk of false positive results.

Watch the Webinar

Smarter Sample Prep: Your workflow from manual processing to automation.

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Make your life easier. Simplify your workflow

Automated sample preparation reduces errors, improves method robustness and frees up laboratory personnel for other tasks.

Automation

Biotage evaporation systems are designed for fast sample evaporation and minimizing sample handling.