The creation of new molecules is fundamental to the drug discovery workflow. Biotage synthesisers include microwave systems for rapid organic chemistry and sequential or parallel peptide synthesisers, all designed to greatly increase the speed and throughput of your chemistry. 

After new molecules have been created, later purification stages can be vastly simplified by removing major impurities, starting materials and other undesirables by workup stages. Biotage offer a wide range of plastic ware and workup solutions from filter funnels to ion exchangers.

Isolating the desired product from a complex mixture requires powerful purification techniques. Biotage have been pioneers in flash chromatography for many years, on both lab and manufacturing scale, and our solutions are considered best in class by our customers.

Finally, isolating a pure product from solvents can be a challenge, especially if complex solvent mixtures with varying composition are present. Biotage's powerful evaporation solutions automate and vastly speed up these processes, making for a much more efficient workflow.

Dr. Ana Perez-Lopez is a postdoctoral fellow in the lab of Prof. Juri Rappsilber at Technische Universität Berlin. She found some time to talk to us about the world of organic synthesis and how Biotage solutions have accelerated their science.

We went to Queens, New York to speak with Dr. Aaron Muth from St. John’s University about his work in cancer research using Biotage lab equipment and specifically the SNAP Bio cartridges. An Assistant Professor of Medicinal Chemistry, Dr. Muth and his research group use our equipment every day. 

This white paper discusses the Biotage organic chemistry workflow. Using the Biotage workflow models have shown that the time taken to produce a target molecule can be reduced by up to eighty percent, allowing project delivery timescales to be reduced accordingly. 

This white paper discusses the challenges in employing chromatography in the manufacturing plant, and presents a practical, scalable and commercially viable approach to chromatographic purification in a chemical production environment.