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    Documents | Automated Extraction of 12 Drugs of Abuse from Human Breast Milk Using EVOLUTE® EXPRESS CX Prior to LC-MS/MS Analysis

    Automated Extraction of 12 Drugs of Abuse from Human Breast Milk Using EVOLUTE® EXPRESS CX Prior to LC-MS/MS Analysis


    This poster shows an extraction protocol for 12 common drugs of abuse (DOA) to be detected in breast milk using mixed-mode polymeric cation exchange solid phase extraction (SPE). Using the combination of reliable automation (on Biotage Extrahera) and SPE sample preparation techniques, a method was developed demonstrating the precision, accuracy, linearity, and sensitivity necessary for a robust quantitative workflow. MSACL NA 2019

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