Biotage offers a range of products for reaction mixture work-up and preparation of organic extracts.
A complete set of tools to speed up traditional work flow processes and also enhance productivity and flexibility in the laboratory. These products range from solid supported reagents and scavengers, including the market leading Biotage Metal Scavengers, through to laboratory essentials, such as tubes, frits and separators, which can improve even the simplest of procedures.
The offer of work-up products spans over a range of techniques and also address throughput requirements from filtration, catch & release, and scavenging cartridges in organic synthesis workflows.
Techniques to choose from:
Catch & release
Scavenging
Fraction concentration
A complete set of tools to speed up traditional work flow processes and also enhance productivity and flexibility in the laboratory. These products range from solid supported reagents and scavengers, including the market leading Biotage Metal Scavengers, through to laboratory essentials, such as tubes, frits and separators, which can improve and inform even the simplest of procedures.
Catch & Release and Scavenging of Basic Compounds
ISOLUTE® SCX-2 is a silica-based media with a chemically bonded propylsulfonic acid functional group. It is used for the isolation of
a wide range of basic compounds using both catch & release and scavenging protocols. ISOLUTE SCX-2 is available packed into SPE
cartridges for flow-through. Using the catch & release approach, basic target compounds can be isolated from a range of reaction mixtures. ISOLUTE SCX-2 cartridges can be used to remove excess basic reagents, allowing neutral or acidic compounds to pass straight through to the collection vessel.
Catch & Release and Scavenging of Acidic Compounds
ISOLUTE® PE-AX is a silica-based sorbent with a chemically bonded quaternary amine functional group. It is used for the isolation of a wide range of acidic compounds using both catch & release and scavenging protocols. ISOLUTE PE-AX is available packed into SPE cartridges for flow-through. Using the catch &
release approach, acidic target compounds can be isolated from a range of reaction mixtures. ISOLUTE PE-AX cartridges can be
used in a scavenging mode to remove excess acidic reagents, allowing neutral or basic compounds to pass straight through to the collection vessel.
Simultaneous Scavenging of Basic and Acidic Compounds
ISOLUTE® PE-AX/SCX-2 is a silica-based media with chemically bonded propylsulfonic acid and quaternary amine functional groups. It is used for the isolation of a wide range of neutral compounds. ISOLUTE PE-AX/SCX-2 is available packed into SPE cartridges flow-through.
Concentration of Prep-LC Fractions Using Catch & Release
ISOLUTE® 103 is a hydroxylated polystyrene divinylbenzene co-polymer. The resin is used for the isolation of a wide range of compounds from prep LC fractions using catch & release protocol. The approach replaces the need for time-consuming evaporation of aqueous based fractions.
The offer of work-up products spans over a range of techniques and also address throughput requirements from filtration, catch & release, and scavenging cartridges in organic synthesis workflows.
Techniques to choose from:
Separation of immiscible organic/aqueous phases
Water removal/Drying
Filtration
A complete set of tools to speed up traditional work flow processes and also enhance productivity and flexibility in the laboratory. These products range from solid supported reagents and scavengers, including the market leading Biotage Metal Scavengers, through to laboratory essentials, such as tubes, frits and separators, which can improve and inform even the simplest of procedures.
ISOLUTE® Phase Separators are used to separate aqueous and chlorinated solvents following liquid-liquid extraction. The proprietary filtration device allows the flow of the organic solvent but holds up the aqueous layer (for up to 24 hours).
Sodium sulfate is commonly used for drying water-immiscible organic solvents. ISOLUTE® Sodium Sulfate Drying Cartridges are a convenient alternative to using the bulk material. The male/female Luer design
allows the cartridge to be placed in-line after the main work-up cartridge. Alternatively, connect to an empty reservoir and load larger volumes of solvent. No need to use additional equipment. Just plug in and filter for instant results. The cartridge contains 2.5 g sodium sulfate and can remove up to 3.5 mL water.
Celite* cartridges are used as a filtration device for removal of “tar” and particulate materials (e.g. catalysts, as first- stage work-up following organic synthesis). The cartridges contain an inert Celite material, a modified diatomaceous earth, with an optimized particle-size distribution for flow-through processing. The cartridge holds up catalysts such as insoluble metal oxides and Pd/C, providing filtrates for subsequent work-up. The retention of the catalyst in a cartridge format minimizes safety issues and cross-contamination, a common problem when the catalyst is captured in an open filtration device such as a sintered funnel.
*Celite is a trademark owned by Johns-Manville Corporation
ISOLUTE® HM-N is a modified form of diatomaceous earth. The support has many uses in reaction work-up, including:
Part No. | Description | Pack Size | List Price | |
---|---|---|---|---|
120-1151-D | 15 mL Frit Inserter | 5 | 60 USD | Add to quote/cart |
120-1151-D | 15 mL Frit Inserter | 5 | 60 USD | Add to quote/cart |
120-1151-J | 150 mL Frit Inserter | 1 | 28 USD | Add to quote/cart |
120-1151-J | 150 mL Frit Inserter | 1 | 28 USD | Add to quote/cart |
120-1151-E | 25 mL Frit Inserter | 1 | 27 USD | Add to quote/cart |
120-1151-E | 25 mL Frit Inserter | 1 | 27 USD | Add to quote/cart |
120-1151-F | 70 mL Frit Inserter | 1 | 27 USD | Add to quote/cart |
120-1151-F | 70 mL Frit Inserter | 1 | 27 USD | Add to quote/cart |
122-2100 | Biotage® FlashVac rack special | 1 | Add to quote/cart | |
122-2100 | Biotage® FlashVac rack special | 1 | Add to quote/cart | |
122-0030 | Biotage® FlashVac silicone lid gasket | 1 | 36 USD | Add to quote/cart |
122-0030 | Biotage® FlashVac silicone lid gasket | 1 | 36 USD | Add to quote/cart |
122-1030 | Biotage® FlashVac-10 19 mm rack | 1 | 254 USD | Add to quote/cart |
122-1030 | Biotage® FlashVac-10 19 mm rack | 1 | 254 USD | Add to quote/cart |
122-0049 | Biotage® FlashVac-10 and -20 glass tank | 1 | 294 USD | Add to quote/cart |
122-0049 | Biotage® FlashVac-10 and -20 glass tank | 1 | 294 USD | Add to quote/cart |
122-0044 | Biotage® FlashVac-10 and -20 rack handle | 1 | 20 USD | Add to quote/cart |
122-0044 | Biotage® FlashVac-10 and -20 rack handle | 1 | 20 USD | Add to quote/cart |
122-0047 | Biotage® FlashVac-10 lid | 1 | 1062 USD | Add to quote/cart |
122-0047 | Biotage® FlashVac-10 lid | 1 | 1062 USD | Add to quote/cart |
122-1034 | Biotage® FlashVac-10 rack for 25 mm tubes | 1 | 234 USD | Add to quote/cart |
122-1034 | Biotage® FlashVac-10 rack for 25 mm tubes | 1 | 234 USD | Add to quote/cart |
122-1036 | Biotage® FlashVac-10 Top/Mid PLATE, 25 mm | 1 | 101 USD | Add to quote/cart |
122-1036 | Biotage® FlashVac-10 Top/Mid PLATE, 25 mm | 1 | 101 USD | Add to quote/cart |
122-1019 | Biotage® FlashVac-10 with 19 mm 10 Position rack | 1 | 1472 USD | Add to quote/cart |
122-1019 | Biotage® FlashVac-10 with 19 mm 10 Position rack | 1 | 1472 USD | Add to quote/cart |
122-1025 | Biotage® FlashVac-10, 10 Ports with 25 mm rack | 1 | 1563 USD | Add to quote/cart |
122-1025 | Biotage® FlashVac-10, 10 Ports with 25 mm rack | 1 | 1563 USD | Add to quote/cart |
122-2061 | Biotage® FlashVac-20 19 mm rack | 1 | 268 USD | Add to quote/cart |
122-2061 | Biotage® FlashVac-20 19 mm rack | 1 | 268 USD | Add to quote/cart |
122-2062 | Biotage® FlashVac-20 25mm rack | 1 | 254 USD | Add to quote/cart |
122-2062 | Biotage® FlashVac-20 25mm rack | 1 | 254 USD | Add to quote/cart |
122-0048 | Biotage® FlashVac-20 lid, complete | 1 | 1062 USD | Add to quote/cart |
122-0048 | Biotage® FlashVac-20 lid, complete | 1 | 1062 USD | Add to quote/cart |
122-2019 | Biotage® FlashVac-20 with 19mm 20 position rack | 1 | 1472 USD | Add to quote/cart |
122-2019 | Biotage® FlashVac-20 with 19mm 20 position rack | 1 | 1472 USD | Add to quote/cart |
122-2025 | Biotage® FlashVac-20 with 25mm 10 position rack | 1 | 1472 USD | Add to quote/cart |
122-2025 | Biotage® FlashVac-20 with 25mm 10 position rack | 1 | 1472 USD | Add to quote/cart |
123-2016 | Biotage® Gravity rack with 16 mm collection tube rack | 1 | 643 USD | Add to quote/cart |
123-2016 | Biotage® Gravity rack with 16 mm collection tube rack | 1 | 643 USD | Add to quote/cart |
123-2019 | Biotage® Gravity rack with 19 mm collection tube rack | 1 | 643 USD | Add to quote/cart |
123-2019 | Biotage® Gravity rack with 19 mm collection tube rack | 1 | 643 USD | Add to quote/cart |
123-2119 | Biotage® Gravity Rack, TOP/MID plate, 19 mm | 1 | 107 USD | Add to quote/cart |
123-2119 | Biotage® Gravity Rack, TOP/MID plate, 19 mm | 1 | 107 USD | Add to quote/cart |
800477-0010-B | Cartridge, MP-TSOH ,0.1 g, 3 mL | 50 | 146 USD | Add to quote/cart |
800477-0010-BG | Cartridge, MP-TSOH, 0.1 g, 3 mL (tabless) | 50 | 160 USD | Add to quote/cart |
800477-0025-C | Cartridge, MP-TSOH, 0.25 g, 6 mL | 30 | 175 USD | Add to quote/cart |
800477-0025-CG | Cartridge, MP-TSOH, 0.25 g, 6 mL (tabless) | 30 | 181 USD | Add to quote/cart |
800477-0050-C | Cartridge, MP-TSOH, 0.5 g, 6 mL | 30 | 206 USD | Add to quote/cart |
800477-0100-D | Cartridge, MP-TSOH, 1 g, 15 mL | 20 | 186 USD | Add to quote/cart |
800477-0050-CG | Cartridge, MP-TSOH, 500 mg, 6 mL (tabless) | 30 | 222 USD | Add to quote/cart |
810-0100-D | Celite 545 1 g/15 mL | 20 | 107 USD | Add to quote/cart |
810-0100-C | Celite 545 1 g/6 mL | 30 | 128 USD | Add to quote/cart |
810-0100-CG | Celite 545 1 g/6 mL (Tabless) | 30 | 142 USD | Add to quote/cart |
810-1000-J | Celite 545 10 g/150 mL | 8 | 101 USD | Add to quote/cart |
810-0250-E | Celite 545 2.5 g/25 mL | 20 | 134 USD | Add to quote/cart |
810-0045-P01 | Celite 545 45 mg plate | 1 | 181 USD | Add to quote/cart |
120-1110 | Flash Luer Lock to Luer Adapters | 25 | 47 USD | Add to quote/cart |
120-1110 | Flash Luer Lock to Luer Adapters | 25 | 47 USD | Add to quote/cart |
103-0200-E | ISOLUTE® 103 2 g/25 mL | 20 | 669 USD | Add to quote/cart |
103-0200-E | ISOLUTE® 103 2 g/25 mL | 20 | 669 USD | Add to quote/cart |
103-0020-BG | ISOLUTE® 103 200 mg/3 mL (Tabless) | 50 | 301 USD | Add to quote/cart |
103-0020-BG | ISOLUTE® 103 200 mg/3 mL (Tabless) | 50 | 301 USD | Add to quote/cart |
103-0020-C | ISOLUTE® 103 200 mg/6 mL | 30 | 160 USD | Add to quote/cart |
103-0020-C | ISOLUTE® 103 200 mg/6 mL | 30 | 160 USD | Add to quote/cart |
103-0020-CG | ISOLUTE® 103 200 mg/6 mL (Tabless) | 30 | 175 USD | Add to quote/cart |
103-0020-CG | ISOLUTE® 103 200 mg/6 mL (Tabless) | 30 | 175 USD | Add to quote/cart |
103-0500-E | ISOLUTE® 103 5 g/25 mL | 20 | 1610 USD | Add to quote/cart |
103-0500-E | ISOLUTE® 103 5 g/25 mL | 20 | 1610 USD | Add to quote/cart |
103-0050-C | ISOLUTE® 103 500 mg/6 mL | 30 | 307 USD | Add to quote/cart |
103-0050-C | ISOLUTE® 103 500 mg/6 mL | 30 | 307 USD | Add to quote/cart |
103-0050-CG | ISOLUTE® 103 500 mg/6 mL (Tabless) | 30 | 320 USD | Add to quote/cart |
103-0050-CG | ISOLUTE® 103 500 mg/6 mL (Tabless) | 30 | 320 USD | Add to quote/cart |
180-0300-P01 | ISOLUTE® 96 Si-Thiol 300 mg plate, Bulk Pack 100 | 100 | 422 USD | Add to quote/cart |
180-0300-P01 | ISOLUTE® 96 Si-Thiol 300 mg plate, Bulk Pack 100 | 100 | 422 USD | Add to quote/cart |
121-9650 | ISOLUTE® Array 24 | 1 | 186 USD | Add to quote/cart |
121-9650 | ISOLUTE® Array 24 | 1 | 186 USD | Add to quote/cart |
121-9660 | ISOLUTE® Array 24 Sealing Caps | 50 | 20 USD | Add to quote/cart |
121-9660 | ISOLUTE® Array 24 Sealing Caps | 50 | 20 USD | Add to quote/cart |
120-1920-T | ISOLUTE® ARRAY Phase separator loose wells 2 mL | 100 | 134 USD | Add to quote/cart |
120-1920-T | ISOLUTE® ARRAY Phase separator loose wells 2 mL | 100 | 134 USD | Add to quote/cart |
120-1920-TP | ISOLUTE® ARRAY PHASE SEPARATOR PLATE 2ML | 1 | 175 USD | Add to quote/cart |
120-1920-TP | ISOLUTE® ARRAY PHASE SEPARATOR PLATE 2ML | 1 | 175 USD | Add to quote/cart |
420-5000-J | ISOLUTE® CN 50 g/150 mL | 8 | 926 USD | Add to quote/cart |
420-7000-J | ISOLUTE® CN 70 g/150 mL | 8 | 1198 USD | Add to quote/cart |
120-1106 | ISOLUTE® Column Adapter 150 mL columns | 5 | 201 USD | Add to quote/cart |
120-1106 | ISOLUTE® Column Adapter 150 mL columns | 5 | 201 USD | Add to quote/cart |
120-1215-D | ISOLUTE® Double Fritted Reservoir (SG), 15 mL 20 µm PE | 100 | 175 USD | Add to quote/cart |
120-1215-D | ISOLUTE® Double Fritted Reservoir (SG), 15 mL 20 µm PE | 100 | 175 USD | Add to quote/cart |
120-1218-J | ISOLUTE® Double Fritted Reservoir (SG), 150 mL 20 µm PE | 25 | 175 USD | Add to quote/cart |
120-1218-J | ISOLUTE® Double Fritted Reservoir (SG), 150 mL 20 µm PE | 25 | 175 USD | Add to quote/cart |
120-1217-F | ISOLUTE® Double Fritted Reservoir (SG), 70 mL 20 µm PE | 50 | 113 USD | Add to quote/cart |
120-1217-F | ISOLUTE® Double Fritted Reservoir (SG), 70 mL 20 µm PE | 50 | 113 USD | Add to quote/cart |
120-1120-K | ISOLUTE® Filtration Column 50 mL | 25 | 186 USD | Add to quote/cart |
120-1120-K | ISOLUTE® Filtration Column 50 mL | 25 | 186 USD | Add to quote/cart |
456-1000-F | ISOLUTE® FLASH SCX-2 10 g/70 mL | 16 | 426 USD | Add to quote/cart |
456-0100-C | ISOLUTE® FLASH SCX-2 1g/6ml | 30 | 169 USD | Add to quote/cart |
456-0200-D | ISOLUTE® FLASH SCX-2 2 g/15 mL | 20 | 169 USD | Add to quote/cart |
456-0200-DG | ISOLUTE® FLASH SCX-2 2 g/15 mL | 20 | 201 USD | Add to quote/cart |
456-2000-F | ISOLUTE® FLASH SCX-2 20 g/70 mL | 16 | 842 USD | Add to quote/cart |
FlashVac Sample Processing Manifolds are used to process the complete range of ISOLUTE work-up columns. The manifolds can be used for Catch & Release and scavenging SPE, filtration, and off-line sample loading prior to flash chromatography.
Biotage offers a range of accessories for use with filtration, Catch & Release, and scavenging SPE columns in organic synthesis work-up schemes.
Accessories include stop-cocks, luer tip caps, cartridge adaptors.
Biotage is a Global Impact Tech Company committed to solving society’s problems. We offer workflow solutions and products to customers in drug discovery and development and diagnostics, analytical testing and water and environmental testing.
Biotage is contributing to sustainable science with the goal to make the world healthier, greener and cleaner – HumanKind Unlimited.
Our customers span a broad range of market segments including pharmaceutical, biotech, diagnostic, contract research and contract manufacturers as well as clinical, forensic and academic laboratories in addition to organizations focused on food safety, clean water and environmental sustainability.
Biotage is headquartered in Uppsala in Sweden and employs appr. 700 people worldwide. The Group had sales of 1,566 MSEK in 2022 and our products are sold in more than 80 countries. Biotage’s share (BIOT) is listed in the Large Cap segment on the NASDAQ Stockholm.
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