Flash chromatography

Advancing compound purity in drug discovery and research

Flash chromatography excels at separating a wide range of compounds effectively. The technique enables the adjustment of multiple variables to reach the desired purity level, ensuring successful flash purification.

Reducing solvent usage effectively

Reducing solvent usage in flash chromatography is critical for environmental and cost reasons. Fortunately, there are effective strategies to achieve this.

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Faster + simpler + greener

Our flash chromatography approach focuses on efficient isolation of target molecules with maximum recovery. Supported by our modular, fully automated Biotage® Selekt systems and Biotage® Sfär pre-packed columns, we can cater to various needs in drug discovery and research laboratories.

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Seamless scale up

Establish optimal flash purification parameters during the development phase to optimize loading, compound purity, and yield. This ensures reproducibility from lab to manufacturing.

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New: Biotage® Selekt ELSD

Efficient detection, ease of use, and robust purification. Our advanced evaporative light-scattering detector has it all. Simply mount the detector on your Biotage® Selekt system to see your compounds clearly.

Related products

Biotage® Selekt

High-performance, versatile flash purification system designed for broad requirements in drug discovery and research laboratories.

Biotage® Selekt Enkel

Automated flash purification system designed for small-scale, focused applications in drug discovery and research laboratories.

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Accessories and Spare Parts

The Selekt family offers a range of accessories designed to enhance system functionality, tailored to meet your specific needs.

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Biotage® Sfär

Reliable and flexible columns that are available in different sizes, media and with specific characteristics.

Large Scale Flash Purification

Large scale systems for the purification of target compounds in scale-up studies, in manufacturing and on the pilot plant.

News from our blog

Optimizing peptide purification with flash chromatography

A study shows flash chromatography efficiently purifies peptides, allowing larger loads per injection while saving time, solvent, and costs versus HPLC.

Does media choice matter for peptide library purification using solid phase extraction?

SPE is emerging as a strategy for peptide library clean up in parallel.

What is the difference between solid vs. liquid particles in ELSD signal?

ELSD is useful for finding molecules that have no chromophore during flash purification. Here we show how signal intensity can vary between compounds!

Documents

Other steps in the organic workflow

Biotage evaporation offer is designed for faster evaporation of volatile and high-boiling solvents and sample transfer minimization. Utilizing rotation and vacuum technology, Biotage will automate your evaporation and make it faster, simpler, greener.

Evaporation

Microwave heating is by far the superior choice for synthesizing novel compounds and can offer advantages other than just speed. Working at temperatures and pressures not attainable through traditional heating, it allows chemists to perform reactions otherwise not possible. Faster, Simpler, Greener.

Organic Synthesis

A complete set of tools to speed up traditional work flow processes and also enhance productivity and flexibility in the laboratory. Faster, Simpler, Greener.

Work-Up