Flash Chromatography
When a step in a molecular is synthesis is completed and workup has been performed, the resultant reaction mixture is often complex containing many chemical species. These include starting materials, catalysts, side product and solvent as well as the target product of the reaction. To progress the synthesis, the product needs to be isolated in sufficient purity for the next step. Traditionally, this has involved column chromatography with a packed glass column, involving solvent addition through the top of the column and gradual elution of the components in a steady solvent from through chromatographic interactions.
